期刊
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
卷 6, 期 1, 页码 349-360出版社
MDPI
DOI: 10.3390/ijerph6010349
关键词
Ethyl carbamate; urethane; alcoholic beverages; risk assessment; Mexico; Guatemala; carcinogens; gas chromatography; mass spectrometry; food contamination; food analysis; sugarcane; agave; tequila; mezcal; cuxa; unrecorded alcohol
Ethyl carbamate (EC) is a recognized genotoxic carcinogen, with widespread occurrence in fermented foods and beverages. No data on its occurrence in alcoholic beverages from Mexico or Central America is available. Samples of agave spirits including tequila, mezcal, bacanora and sotol (n=110), and of the sugarcane spirit cuxa (n=16) were purchased in Mexico and Guatemala, respectively, and analyzed for EC. The incidence of EC contamination was higher in Mexico than in Guatemala, however, concentrations were below international guideline levels (< 0.15 mg/L). Risk assessment found the Margin of Exposure (MOE) in line with that of European spirits. It is therefore unlikely that EC plays a role in high rates of liver cirrhosis reported in Mexico.
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