期刊
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY
卷 9, 期 1, 页码 46-52出版社
WILEY
DOI: 10.1002/alr.22196
关键词
sinusitis; chronic disease; machine learning; neural network; convolutional neural network
资金
- NIH (National Institute on Deafness and Other Communication Disorders [NIDCD]) [R01 DC005805, RO3 DC014809]
- NIH (National Institute of Allergy and Infectious Diseases [NIAID]) [L30 AI113795]
- NIH (National Center for Advancing Translational Sciences [NCATS] Clinical and Translational Science Awards [CTSA]) [UL1TR000445]
Background Convolutional neural networks (CNNs) are advanced artificial intelligence algorithms well suited to image classification tasks with variable features. These have been used to great effect in various real-world applications including handwriting recognition, face detection, image search, and fraud prevention. We sought to retrain a robust CNN with coronal computed tomography (CT) images to classify osteomeatal complex (OMC) occlusion and assess the performance of this technology with rhinologic data. Methods The Google Inception-V3 CNN trained with 1.28 million images was used as the base model. Preoperative coronal sections through the OMC were obtained from 239 patients enrolled in 2 prospective chronic rhinosinusitis (CRS) outcomes studies, labeled according to OMC status, and mirrored to obtain a set of 956 images. Using this data, the classification layer of Inception-V3 was retrained in Python using a transfer learning method to adapt the CNN to the task of interpreting sinonasal CT images. Results The retrained neural network achieved 85% classification accuracy for OMC occlusion, with a 95% confidence interval for algorithm accuracy of 78% to 92%. Receiver operating characteristic (ROC) curve analysis on the test set confirmed good classification ability of the CNN with an area under the ROC curve (AUC) of 0.87, significantly different than both random guessing and a dominant classifier that predicts the most common class (p < 0.0001). Conclusion Current state-of-the-art CNNs may be able to learn clinically relevant information from 2-dimensional sinonasal CT images with minimal supervision. Future work will extend this approach to 3-dimensional images in order to further refine this technology for possible clinical applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据