期刊
HUMAN VACCINES & IMMUNOTHERAPEUTICS
卷 9, 期 5, 页码 1073-1077出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/hv.23587
关键词
CD4 T cell; helper peptide; telomerase; cancer vaccine
资金
- Ligue Contre le Cancer
- Association pour la Recherche contre le Cancer, France
- province of Franche Comte, France
Current cancer immunotherapies predominantly rely on CD8(+) T cells to fight against tumors. However accumulative evidence showed that proinflammatory CD4(+) helper T cells are critical determinants of effective antitumor immunity. The utilization of universal tumor-reactive helper peptides from telomerase represents a powerful approach to the fully use of CD4(+) T cell-based immunotherapy.
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