期刊
GENOME MEDICINE
卷 3, 期 -, 页码 -出版社
BIOMED CENTRAL LTD
DOI: 10.1186/gm279
关键词
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资金
- Academy of Finland (Centres of Excellence) [213502]
- Cancer Organizations of Finland Sigdrid Juselius Foundation
- Cancer Organizations of Finland
- Helsinki University funds
We present a new method to analyze cancer of unknown primary origin (CUP) samples. Our method achieves good results with classification accuracy (88% leave-one-out cross validation for primary tumors from 56 categories, 78% for CUP samples), and can also be used to study CUP samples on a gene-by-gene basis. It is not tied to any a priori defined gene set as many previous methods, and is adaptable to emerging new information.
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