期刊
G3-GENES GENOMES GENETICS
卷 4, 期 3, 页码 389-398出版社
GENETICS SOCIETY AMERICA
DOI: 10.1534/g3.113.008995
关键词
S288C; Saccharomyces cerevisiae; genome release; model organism; reference sequence
资金
- U41 grant from the National Human Genome Research Institute at the U.S. National Institutes of Health [HG001315]
The genome of the budding yeast Saccharomyces cerevisiae was the first completely sequenced from a eukaryote. It was released in 1996 as the work of a worldwide effort of hundreds of researchers. In the time since, the yeast genome has been intensively studied by geneticists, molecular biologists, and computational scientists all over the world. Maintenance and annotation of the genome sequence have long been provided by the Saccharomyces Genome Database, one of the original model organism databases. To deepen our understanding of the eukaryotic genome, the S. cerevisiae strain S288C reference genome sequence was updated recently in its first major update since 1996. The new version, called S288C 2010, was determined from a single yeast colony using modern sequencing technologies and serves as the anchor for further innovations in yeast genomic science.
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