期刊
CURRENT OPINION IN VIROLOGY
卷 4, 期 -, 页码 8-14出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2013.10.002
关键词
-
类别
资金
- Ambizione [PZ00P3_131988]
- Swiss National Foundation InfectX [232974]
- ERC [232974]
- European Research Council (ERC) [232974] Funding Source: European Research Council (ERC)
- Swiss National Science Foundation (SNF) [PZ00P3_131988] Funding Source: Swiss National Science Foundation (SNF)
As obligate intracellular parasites viruses rely on host cell factors and functions for all stages of infection, from entry to spread. Characterization of these cellular components is critical to advance our understanding of the infection process and develop novel means to combat viral pathogens. To this end, the recent application of next generation approaches including compound screening, cell-targeting RNA interference, gene knockouts, and several proteomics approaches has served to expand our understanding of virus-host interactions, and facilitated the discovery of potential antiviral targets. Here we review recent progress in the use of these next generation approaches and discuss their challenges, pitfalls, and potential applications for the study of virus-host interplay.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据