4.5 Article

Ebolavirus vaccines for humans and apes

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CURRENT OPINION IN VIROLOGY
卷 2, 期 3, 页码 324-329

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ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2012.04.003

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  1. Intramural NIH HHS [ZIA AI005082-07, ZIA AI005081-07, ZIA AI005081-05, ZIA AI005082-06, Z01 AI005079-03, ZIA AI005079-05, ZIA AI005082-05, ZIA AI005081-06, Z01 AI005082-03, Z01 AI005081-03] Funding Source: Medline

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Because of high case fatality proportions, person-to-person transmission, and potential use in bioterrorism, the development of a vaccine against ebolavirus remains a top priority. Although no licensed vaccine or treatment against ebolavirus is currently available, progress in preclinical testing of countermeasures has been made. Here, we will review ebolavirus vaccine candidates and considerations for their use in humans and wild apes.

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