相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Diverse roles of the ubiquitin system in NF-κB activation
Kazuhiro Iwai
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs
Cecilia A. Hinojosa et al.
EXPERIMENTAL GERONTOLOGY (2014)
Astrocytes Play a Key Role in EAE Pathophysiology by Orchestrating in the CNS the Inflammatory Response of Resident and Peripheral Immune Cells and by Suppressing Remyelination
Roberta Brambilla et al.
GLIA (2014)
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: Crosstalk between NF-κB and PPAR-γ
Youzhi Zhang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Monocytes and CD4+ T cells contribution to the under-expression of NR4A2 and TNFAIP3 genes in patients with multiple sclerosis
N. D. Navone et al.
JOURNAL OF NEUROIMMUNOLOGY (2014)
Immunostaining of Oxidized DJ-1 in Human and Mouse Brains
Yoshiro Saito et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2014)
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
Nathaniel S. Woodling et al.
JOURNAL OF NEUROSCIENCE (2014)
MS and related disorders: groundbreaking news
Emmanuelle Waubant et al.
LANCET NEUROLOGY (2014)
Acquired Deficiency of A20 Results in Rapid Apoptosis, Systemic Inflammation, and Abnormal Hematopoietic Stem Cell Function
Akiko Nagamachi et al.
PLOS ONE (2014)
Multiple sclerosis in the context of TNF blockade and inflammatory bowel disease
N. C. Hare et al.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2014)
A20 in inflammation and autoimmunity
Leen Catrysse et al.
TRENDS IN IMMUNOLOGY (2014)
Astrocytic A20 ameliorates experimental autoimmune encephalomyelitis by inhibiting NF-κB- and STAT1-dependent chemokine production in astrocytes
Xu Wang et al.
ACTA NEUROPATHOLOGICA (2013)
Tumor Necrosis Factor Induces Sustained Signaling and a Prolonged and Unremitting Inflammatory Response in Rheumatoid Arthritis Synovial Fibroblasts
Angela Lee et al.
ARTHRITIS AND RHEUMATISM (2013)
Cezanne Regulates Inflammatory Responses to Hypoxia in Endothelial Cells by Targeting TRAF6 for Deubiquitination
Le A. Luong et al.
CIRCULATION RESEARCH (2013)
A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease
Han-Yun Hsiao et al.
HUMAN MOLECULAR GENETICS (2013)
Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like Skin Inflammation in Mice
Snehlata Kumari et al.
IMMUNITY (2013)
Cutting Edge: ABIN-1 Protects against Psoriasis by Restricting MyD88 Signals in Dendritic Cells
Joseph A. Callahan et al.
JOURNAL OF IMMUNOLOGY (2013)
Paracaspase MALT1 Deficiency Protects Mice from Autoimmune-Mediated Demyelination
Conor Mc Guire et al.
JOURNAL OF IMMUNOLOGY (2013)
Opposing Action of Nuclear Factor κB and Polo-like Kinases Determines a Homeostatic End Point for Excitatory Synaptic Adaptation
Anca B. Mihalas et al.
JOURNAL OF NEUROSCIENCE (2013)
Interaction and Antagonistic Roles of NF-κB and Hes6 in the Regulation of Cortical Neurogenesis
Laurent Methot et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO
Anne Kathrin Mueller-Rischart et al.
MOLECULAR CELL (2013)
Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging
Ayesha Maqbool et al.
MOLECULAR NEURODEGENERATION (2013)
Multiple sclerosis risk genotypes correlate with an elevated cerebrospinal fluid level of the suggested prognostic marker CXCL13
M. Linden et al.
MULTIPLE SCLEROSIS JOURNAL (2013)
OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3
Hongbo Hu et al.
NATURE (2013)
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Ashley H. Beecham et al.
NATURE GENETICS (2013)
NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease
Elaine Pranski et al.
NEUROSCIENCE LETTERS (2013)
The Deubiquitinase A20 Mediates Feedback Inhibition of Interleukin-17 Receptor Signaling
Abhishek V. Garg et al.
SCIENCE SIGNALING (2013)
Regulation of nuclear factor-κB in autoimmunity
Shao-Cong Sun et al.
TRENDS IN IMMUNOLOGY (2013)
NF-κB p50 subunit knockout impairs late LTP and alters long term memory in the mouse hippocampus
Kensuke Oikawa et al.
BMC NEUROSCIENCE (2012)
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice
Cristina Baiguera et al.
BRAIN (2012)
Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20
Megumi Inomata et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Putting together the psoriasis puzzle: an update on developing targeted therapies
Leanne M. Johnson-Huang et al.
DISEASE MODELS & MECHANISMS (2012)
Nuclear Factor-κB Regulates βAPP and β- and γ-Secretases Differently at Physiological and Supraphysiological Aβ Concentrations
Linda Chami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells
Anne Bruestle et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis
Trilokraj Tejasvi et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities
Esteban Braggio et al.
MODERN PATHOLOGY (2012)
RNF11 modulates microglia activation through NF-κB signalling cascade
Nirjari V. Dalal et al.
NEUROSCIENCE LETTERS (2012)
A20: linking a complex regulator of ubiquitylation to immunity and human disease
Averil Ma et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Loss of Braking Signals During Inflammation A Factor Affecting the Development and Disease Course of Multiple Sclerosis
Francesca Gilli et al.
ARCHIVES OF NEUROLOGY (2011)
The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway
Marija Cemma et al.
AUTOPHAGY (2011)
B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice
Yuanyuan Chu et al.
BLOOD (2011)
Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis
S. Lippens et al.
CELL DEATH AND DIFFERENTIATION (2011)
Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases
S. L. Musone et al.
GENES AND IMMUNITY (2011)
The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity
Mirjam Kool et al.
IMMUNITY (2011)
DJ-1 Enhances Cell Survival through the Binding of Cezanne, a Negative Regulator of NF-κB
R. Sean Mcnally et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Tumor suppressor TNFAIP3 (A20) is frequently deleted in Sezary syndrome
F. C. M. Braun et al.
LEUKEMIA (2011)
A potential mechanism of rituximab-induced inhibition of tumor growth through its sensitization to tumor necrosis factor-related apoptosis-inducing ligand-expressing host cytotoxic cells
Mario I. Vega et al.
LEUKEMIA & LYMPHOMA (2011)
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
Mourad Matmati et al.
NATURE GENETICS (2011)
The Association of a Nonsynonymous Single-Nucleotide Polymorphism in TNFAIP3 With Systemic Lupus Erythematosus and Rheumatoid Arthritis in the Japanese Population
Kenichi Shimane et al.
ARTHRITIS AND RHEUMATISM (2010)
A20 inhibition of NFκB and inflammation Targeting E2:E3 ubiquitin enzyme complexes
Noula Shembade et al.
CELL CYCLE (2010)
Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation
M. Won et al.
CELL DEATH AND DIFFERENTIATION (2010)
Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis
John Bowes et al.
HUMAN GENETICS (2010)
The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus
Edoardo Marcora et al.
HUMAN MOLECULAR GENETICS (2010)
A20 is targeted by promoter methylation, deletion and inactivating mutation in MALT lymphoma
E. Chanudet et al.
LEUKEMIA (2010)
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
Amy Strange et al.
NATURE GENETICS (2010)
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne
Anja Bremm et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
TRAF6 and A20 Regulate Lysine 63-Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy
Chong-Shan Shi et al.
SCIENCE SIGNALING (2010)
Signaling to NF-κB: Regulation by Ubiquitination
Ingrid E. Wertz et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth
Anita B. Hjelmeland et al.
PLOS BIOLOGY (2010)
A20: from ubiquitin editing to tumour suppression
Sarah G. Hymowitz et al.
NATURE REVIEWS CANCER (2010)
The NF-κB negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas
Urban Novak et al.
BLOOD (2009)
TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas
Keiichiro Honma et al.
BLOOD (2009)
RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair
Jingxin Wang et al.
EMBO REPORTS (2009)
A20 is overexpressed in glioma cells and may serve as a potential therapeutic target
Qingdong Guo et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
A20: Central Gatekeeper in Inflammation and Immunity
Beatrice Coornaert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A20 takes on tumors: tumor suppression by an ubiquitin-editing enzyme
Barbara A. Malynn et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
Roland Schmitz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
A20 Negatively Regulates T Cell Receptor Signaling to NF-κB by Cleaving Malt1 Ubiquitin Chains
Michael Duewel et al.
JOURNAL OF IMMUNOLOGY (2009)
NF-kappa B p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia
Ilenia Sarnico et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype
George P. Christophi et al.
LABORATORY INVESTIGATION (2009)
Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma
Mara Compagno et al.
NATURE (2009)
Frequent inactivation of A20 in B-cell lymphomas
Motohiro Kato et al.
NATURE (2009)
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
Vesela Gateva et al.
NATURE GENETICS (2009)
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
Philip L. De Jager et al.
NATURE GENETICS (2009)
Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways
Rajan P. Nair et al.
NATURE GENETICS (2009)
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
Teresa L. M. Thurston et al.
NATURE IMMUNOLOGY (2009)
Mechanisms of Disease: Psoriasis.
Frank O. Nestle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology
Lars Vereecke et al.
TRENDS IN IMMUNOLOGY (2009)
Structure and signalling in the IL-17 receptor family (vol 9, pg 556, 2009)
Sarah L. Gaffen
NATURE REVIEWS IMMUNOLOGY (2009)
TNFAIP3 is the target gene of chromosome band 6q23.3-q24.1 loss in ocular adnexal marginal zone B cell lymphoma
Keiichiro Honma et al.
GENES CHROMOSOMES & CANCER (2008)
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
Osamu Hitotsumatsu et al.
IMMUNITY (2008)
Signaling mechanisms involved in the response to genotoxic stress and regulating lifespan
Laura J. Niedemhofer et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
NF-κB suppression by the deubiquitinating enzyme Cezanne -: A novel negative feedback loop in pro-inflammatory signaling
Karine Enesa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
Yongjie Wei et al.
MOLECULAR CELL (2008)
Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
Stacy L. Musone et al.
NATURE GENETICS (2008)
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-κB inhibitor A20
Beatrice Coornaert et al.
NATURE IMMUNOLOGY (2008)
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
Bjoern Schumacher et al.
PLOS GENETICS (2008)
Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity
Andres Kriete et al.
Immunity & Ageing (2008)
Motif module map reveals enforcement of aging by continual NF-κB activity
Adam S. Adler et al.
GENES & DEVELOPMENT (2007)
Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
Anamitra Ghosh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Malt1 ubiquitination triggers NF-κB signaling upon T-cell activation
Andrea Oeckinghaus et al.
EMBO JOURNAL (2007)
PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain
Leah R. Anderson et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Interleukin-1-induced NF-κB activation is NEMO-dependent but does not require IKKβ
Laura A. Solt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Pathogenesis and therapy of psoriasis
Michelle A. Lowes et al.
NATURE (2007)
NF-κB as a therapeutic target in neurodegenerative diseases
Simonetta Camandola et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
NF-κB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity
Alison O'Mahony et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice
Geert van Loo et al.
NATURE IMMUNOLOGY (2006)
A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages
Hong-Liang Li et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
ABIN-1 binds to NEMO/IKKγ and co-operates with A20 in inhibiting NF-κB
Claudio Mauro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A loss-of-function RNA interference screen for molecular targets in cancer
VN Ngo et al.
NATURE (2006)
Roles for NF-κB in nerve cell survival, plasticity, and disease
MP Mattson et al.
CELL DEATH AND DIFFERENTIATION (2006)
Synaptic plasticity in the hippocampus: Effects of estrogen from the gonads or hippocampus?
GM Rune et al.
NEUROCHEMICAL RESEARCH (2006)
Tumor necrosis factor-α-induced protein 3 as a putative regulator of nuclear factor-κB-mediated resistance to O6-alkylating agents in human glioblastomas
M Bredel et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Neuroprotective effect of a20 on TNF-induced postischemic apoptosis
LY Yu et al.
NEUROCHEMICAL RESEARCH (2006)
Expression of the tumor necrosis factor receptor-associated factors I and 2 and regulation of the nuclear factor-κB antiapoptotic activity in human gliomas
A Conti et al.
JOURNAL OF NEUROSURGERY (2005)
Signaling via NF-κB in the nervous system
B Kaltschmidt et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)
Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity
PC Evans et al.
BIOCHEMICAL JOURNAL (2004)
Involvement of Rd/nuclear factor-κB transcription factors in keratinocyte senescence
D Bernard et al.
CANCER RESEARCH (2004)
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
IE Wertz et al.
NATURE (2004)
Antineuroinflammatory effect of NK-κB essential modifer-binding domain peptides in the adoptive transfer model of experimental allergic enchepalomyelitis
S Dasgupta et al.
JOURNAL OF IMMUNOLOGY (2004)
Nuclear factor (NF)-κB proteins:: therapeutic targets
IM Verma
ANNALS OF THE RHEUMATIC DISEASES (2004)
A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation
S Daniel et al.
BLOOD (2004)
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
DL Boone et al.
NATURE IMMUNOLOGY (2004)
NF-κB functions in synaptic signaling and behavior
MK Meffert et al.
NATURE NEUROSCIENCE (2003)
A role for NF-κB essential modifier/IκB kinase-γ (NEMO/IKKγ) ubiquitination in the activation of the IκB kinase complex by tumor necrosis factor-α
ED Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis
CR Longo et al.
CIRCULATION (2003)
Aging and genome maintenance: Lessons from the mouse?
P Hasty et al.
SCIENCE (2003)
Differential requirement for Malt1 in T and B cell antigen receptor signaling
J Ruland et al.
IMMUNITY (2003)
A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor I complex in Jurkat T cells
KL He et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
M Pasparakis et al.
NATURE (2002)
Recent advances in understanding NF-κB regulation
DL Boone et al.
INFLAMMATORY BOWEL DISEASES (2002)
Isolation and characterization of two novel A20-like proteins
PC Evans et al.
BIOCHEMICAL JOURNAL (2001)
A20 zinc finger protein inhibits TNF-induced apoptosis and stress response early in the signaling cascades and independently of binding to TRAF2 or 14-3-3 proteins
U Lademann et al.
CELL DEATH AND DIFFERENTIATION (2001)
Cerebral ischemia and inflammation
C Iadecola et al.
CURRENT OPINION IN NEUROLOGY (2001)
A20 and A20-binding proteins as cellular inhibitors of nuclear factor-κB-dependent gene expression and apoptosis
R Beyaert et al.
BIOCHEMICAL PHARMACOLOGY (2000)
Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
L Deng et al.
CELL (2000)
Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice
EG Lee et al.
SCIENCE (2000)
A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniae
KS Makarova et al.
TRENDS IN BIOCHEMICAL SCIENCES (2000)
分享论文
