期刊
AIP ADVANCES
卷 2, 期 2, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4733346
关键词
-
资金
- key discipline of Zhejiang province
- Natural Science Foundation of Zhejiang province
- Ningbo municipal in China [Xkl11077, Y1080118, 2011A610108]
This paper describes the use of a printed circuit technology to generate hydrophilic channels in a filter paper. Patterns of channels were designed using Protel soft, and printed on a blank paper. Then, the patterns were transferred to a sheet copper using a thermal transfer printer. The sheet copper with patterns was dipped into ferric chloride solution to etch the whole patterns of the sheet copper. At last, the etched sheet copper was coated with a film of paraffin and then a filter paper. An electric iron was used to heat the other side of the sheet copper. The melting paraffin penetrated full thickness of the filter paper and formed a hydrophobic wall. Colorimetric assays for the presence of protein and glucose were demonstrated using the paper-based device. The work is helpful to researchers to fabricate paper-based microfluidic devices for monitoring health and detecting disease. Copyright 2012 Author(s). This article is distributed under a Creative Commons Attribution 3.0 Unported License. [http://dx.doi.org/10.1063/1.4733346]
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