期刊
THERANOSTICS
卷 3, 期 2, 页码 109-115出版社
IVYSPRING INT PUBL
DOI: 10.7150/thno.5133
关键词
Near infrared quantum dots; Bioimaging; Surface functionalization; Targeted delivery; Nanotoxicity
资金
- Changchun University of Science and Technology
- Singapore Ministry of Education [MOE2010-T2-2-010, M4020020.040 ARC2/11, M4010360.040 RG29/10]
- Nanyang Technological University [M4080141.040]
- Beijing Natural Science Foundation [7092097]
- National Natural Science Foundation of China [21071150]
Near infrared quantum dots have been receiving great attention as fluorescent optical probes for in vivo imaging applications. In this contribution, we report the synthesis and surface functionalization of cadmium free ternary AgInS2 nanocrystals emitting in the near infrared range for successful in vitro and in vivo bioimaging applications. The FDA approved triblock copolymer Pluronic F127 was used to encapsulate the nanocrystals and made them dispersible in aqueous solution. By employing a whole body small animal optical imaging setup, we were able to use the AgInS2 nanocrystals formulation for passive targeted delivery to the tumor site. The ultra-small crystal size, near-infrared emitting luminescence, and high quantum yield make the AgInS2 nanocrystals an attractive candidate as a biological contrast agent for cancer sensing and imaging.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据