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VIRUSES-BASEL (2016)
Nucleosome breathing and remodeling constrain CRISPR-Cas9 function
R. Stefan Isaac et al.
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Software for the analysis and visualization of deep mutational scanning data
Jesse D. Bloom
BMC BIOINFORMATICS (2015)
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Bernd Zetsche et al.
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Nicolas Wyvekens et al.
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Enbo Ma et al.
MOLECULAR CELL (2015)
Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems
Sergey Shmakov et al.
MOLECULAR CELL (2015)
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
Benjamin P. Kleinstiver et al.
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Samuel H. Sternberg et al.
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F. Ann Ran et al.
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Mehmet Fatih Bolukbasi et al.
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Massively parallel single-amino-acid mutagenesis
Jacob O. Kitzman et al.
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Hiroshi Nishimasu et al.
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Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
Carolin Anders et al.
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John P. Guilinger et al.
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Deep mutational scanning: a new style of protein science
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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
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DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
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Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
Kevin M. Esvelt et al.
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Zhonggang Hou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
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Prashant Mali et al.
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Le Cong et al.
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Martin Jinek et al.
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Preparation of highly efficient electrocompetent Escherichia coli using glycerol/mannitol density step centrifugation
David J. Warren
ANALYTICAL BIOCHEMISTRY (2011)
Design, construction and characterization of a set of insulated bacterial promoters
Joseph H. Davis et al.
NUCLEIC ACIDS RESEARCH (2011)
Mathematical expressions useful in the construction, description and evaluation of protein libraries
AD Bosley et al.
BIOMOLECULAR ENGINEERING (2005)