期刊
SCIENTIFIC REPORTS
卷 7, 期 -, 页码 -出版社
NATURE PORTFOLIO
DOI: 10.1038/s41598-017-07650-6
关键词
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资金
- DUPAN Foundation
- Dutch Ministry of Economic Affairs [KB-21-001-001]
- Austrian Science Foundation [FWF P26363-B25]
- European Union's Horizon research and innovation programme under Marie Sklodowska-Curie Actions: Innovative Training Network IMPRESS [642893]
- ZonMW/DTL
- CNRS
- Generade, the Leiden Centre of Expertise in Genomics
We have sequenced the genome of the endangered European eel using the MinION by Oxford Nanopore, and assembled these data using a novel algorithm specifically designed for large eukaryotic genomes. For this 860 Mbp genome, the entire computational process takes two days on a single CPU. The resulting genome assembly significantly improves on a previous draft based on short reads only, both in terms of contiguity (N50 1.2 Mbp) and structural quality. This combination of affordable nanopore sequencing and light weight assembly promises to make high-quality genomic resources accessible for many non-model plants and animals.
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