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Xiaomin Yin et al.
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JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1 and Cyclin D1 and induces cell cycle exit and neuronal differentiation
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CELL CYCLE (2014)
Tumor Suppressor DYRK1A Effects on Proliferation and Chemoresistance of AML Cells by Downregulating c-Myc
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PLOS ONE (2014)
Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-κB in the pathogenesis of Down syndrome
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BMC MEDICAL GENOMICS (2013)
Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells
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Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A
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NEUROBIOLOGY OF DISEASE (2013)
Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice
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JOURNAL OF NEUROSCIENCE RESEARCH (2012)
In Vivo Analysis of MEF2 Transcription Factors in Synapse Regulation and Neuronal Survival
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REST Regulates DYRK1A Transcription in a Negative Feedback Loop
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages
Sebastiaan M. Bol et al.
PLOS ONE (2011)
Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells
Odessa Yabut et al.
JOURNAL OF NEUROSCIENCE (2010)
Cognitive deficits and associated neurological complications in individuals with Down's syndrome
Ira T. Lott et al.
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Overexpression of Dyrk1A Causes the Defects in Synaptic Vesicle Endocytosis
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Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways
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FASEB JOURNAL (2009)
Molecular genetic analysis of Down syndrome
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HUMAN GENETICS (2009)
The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development
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EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome
Fei Liu et al.
FASEB JOURNAL (2008)
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease
Soo-Ryoon Ryoo et al.
JOURNAL OF NEUROCHEMISTRY (2008)
MEF2: a central regulator of diverse developmental programs
Matthew J. Potthoff et al.
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DYRK1A-mediated hyperphosphorylation of Tau - A functional link between Down syndrome and Alzheimer disease
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
MEF2D expression increases during neuronal differentiation of neural progenitor cells and correlates with neurite length
Brian Yee Hong Lam et al.
NEUROSCIENCE LETTERS (2007)
DYRKIA BAC transgenic mice show altered synaptic plasticity with learning and memory defects
Kyoung-Jin Ahn et al.
NEUROBIOLOGY OF DISEASE (2006)
Motor development and neuropsychological patterns in persons with Down syndrome
Stefano Vicari
BEHAVIOR GENETICS (2006)
Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes
XL Sun et al.
FASEB JOURNAL (2005)
Myocyte enhancer factor-2 transcription factors in neuronal differentiation and survival
KA Heidenreich et al.
MOLECULAR NEUROBIOLOGY (2004)
Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions
B Hämmerle et al.
DEVELOPMENTAL BIOLOGY (2002)
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome
X Altafaj et al.
HUMAN MOLECULAR GENETICS (2001)
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bε at Ser539 and the microtubule-associated protein tau at Thr212:: potential role for DYRK as a glycogen synthase kinase 3-priming kinase
YL Woods et al.
BIOCHEMICAL JOURNAL (2001)
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