4.7 Article

Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

X-ray structures define human P2X3 receptor gating cycle and antagonist action

Steven E. Mansoor et al.

NATURE (2016)

Article Multidisciplinary Sciences

Structure-based discovery of opioid analgesics with reduced side effects

Aashish Manglik et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels

Rebecca C. Allsopp et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Review Pharmacology & Pharmacy

The P2X7 Receptor Channel: Recent Developments and the Use of P2X7 Antagonists in Models of Disease

Rachael Bartlett et al.

PHARMACOLOGICAL REVIEWS (2014)

Article Chemistry, Physical

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

Daniel R. Roe et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)

Article Neurosciences

P2X7 Receptor Channels Allow Direct Permeation of Nanometer-Sized Dyes

Liam E. Browne et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Biochemical Research Methods

Small-molecule ligand docking into comparative models with Rosetta

Steven A. Combs et al.

NATURE PROTOCOLS (2013)

Article Biochemical Research Methods

FTSite: high accuracy detection of ligand binding sites on unbound protein structures

Chi-Ho Ngan et al.

BIOINFORMATICS (2012)

Article Oncology

Expression of P2X7 Receptor Increases In Vivo Tumor Growth

Elena Adinolfi et al.

CANCER RESEARCH (2012)

Article Multidisciplinary Sciences

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Motoyuki Hattori et al.

NATURE (2012)

Article Biochemistry & Molecular Biology

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

Robert E. Sorge et al.

NATURE MEDICINE (2012)

Review Biochemistry & Molecular Biology

Molecular and functional properties of P2X receptors-recent progress and persisting challenges

Karina Kaczmarek-Hajek et al.

PURINERGIC SIGNALLING (2012)

Article Biochemical Research Methods

MDpocket: open-source cavity detection and characterization on molecular dynamics trajectories

Peter Schmidtke et al.

BIOINFORMATICS (2011)

Article Biochemistry & Molecular Biology

The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels

Rebecca C. Allsopp et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Microbiology

The Role of the P2X7 Receptor in Infectious Diseases

Catherine M. Miller et al.

PLOS PATHOGENS (2011)

Review Biochemistry & Molecular Biology

The P2X7 purinergic receptor: from physiology to neurological disorders

Stephen D. Skaper et al.

FASEB JOURNAL (2010)

Article Biochemistry & Molecular Biology

C-terminal Calmodulin-binding Motif Differentially Controls Human and Rat P2X7 Receptor Current Facilitation

Sebastien Roger et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Chemistry, Medicinal

Antagonists of the P2X7 Receptor. From Lead Identification to Drug Development

Simon D. Guile et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

ROSETTALIGAND Docking with Full Ligand and Receptor Flexibility

Ian W. Davis et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

Toshimitsu Kawate et al.

NATURE (2009)

Article Pharmacology & Pharmacy

Direct labelling of the human P2X7 receptor and identification of positive and negative cooperativity of binding

A. D. Michel et al.

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Review Biochemistry & Molecular Biology

Statistical potential for assessment and prediction of protein structures

Min-Yi Shen et al.

PROTEIN SCIENCE (2006)

Article Multidisciplinary Sciences

The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts

Pierre Savi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Physiology

Molecular physiology of P2X receptors

RA North

PHYSIOLOGICAL REVIEWS (2002)