The Effect of Laparoscopic Gastric Plication Surgery on Body Composition, Resting Energy Expenditure, Thyroid Hormones, and Physical Activity in Morbidly Obese Patients

Introduction: Laparoscopic gastric placation (LGP) is one of the innovative bariatric surgeries for weight loss. Several studies have shown that after LGP, resting energy expenditure (REE) has decreased may be as a result of changes in free-fat mass (FFM) and thyroid stimulating hormone (TSH) level. The aim of this study was to assess the changes in body composition, REE, and thyroid hormones in patients undergoing LGP between baseline and 3 months after LGP compared to controls. Methods: This study was performed on 42 patients (21 patients undergoing LGP and 21 age- and weight-matched subjects as controls). Weight, body mass index, body composition, resting metabolic rate, and thyroid hormones are measured at baseline in case and 3 months after the surgery in case and control groups. Results: The patients lost an average of 22.384.00kg weight and fat mass (FM), FFM, and REE decreased after surgery. An increase in T4 and a reduction of T3 and TSH at 3 months after LGP observed that was significant only in T4. The FM was higher and FFM was lower in cases compared to controls. REE (measured and estimated) was lower in cases compared to controls. Conclusion: In this study, we observed a significant difference for REE between obese patients after the surgery and controls, as well as between prior surgery and postsurgery.