相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Identifying compound efficacy targets in phenotypic drug discovery
Markus Schirle et al.
DRUG DISCOVERY TODAY (2016)
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
Richard M. Deans et al.
NATURE CHEMICAL BIOLOGY (2016)
Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma
Ugur Eskiocak et al.
NATURE COMMUNICATIONS (2016)
Cardiac glycosides display selective efficacy for STK11 mutant lung cancer
Nayoung Kim et al.
SCIENTIFIC REPORTS (2016)
Identification of the determinants of 2-deoxyglucose sensitivity in cancer cells by shRNA library screening
Hiroki Kobayashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Functional genomics to uncover drug mechanism of action
Sebastian M. B. Nijman
NATURE CHEMICAL BIOLOGY (2015)
Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma
Narayana Yeddula et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Ouabain elicits human glioblastoma cells apoptosis by generating reactive oxygen species in ERK-p66SHC-dependent pathway
Xiaofei Yan et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
A Perspective on the Future of High-Throughput RNAi Screening: Will CRISPR Cut Out the Competition or Can RNAi Help Guide the Way?
Jessica Taylor et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
被撤回的出版物: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule (Retracted article. See vol. 170, pg. 407, 2017)
Satish Srinivas Kitambi et al.
CELL (2014)
RNAi screening comes of age: improved techniques and complementary approaches
Stephanie E. Mohr et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens
Christina J. Matheny et al.
CHEMISTRY & BIOLOGY (2013)
Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site
Mette Laursen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nanomolar ouabain elicits apoptosis through a direct action on HeLa cell Cross Mark mitochondria
Elba Alonso et al.
STEROIDS (2013)
Transcript Profiling and RNA Interference as Tools To Identify Small Molecule Mechanisms and Therapeutic Potential
Rahul Palchaudhuri et al.
ACS CHEMICAL BIOLOGY (2011)
A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference
Prem K. Premsrirut et al.
CELL (2011)
Marine Natural Product Aurilide Activates the OPA1-Mediated Apoptosis by Binding to Prohibitin
Shin-ichi Sato et al.
CHEMISTRY & BIOLOGY (2011)
Correlating Phosphatidylinositol 3-Kinase Inhibitor Efficacy with Signaling Pathway Status: In silico and Biological Evaluations
Shingo Dan et al.
CANCER RESEARCH (2010)
DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
Yves Pommier et al.
CHEMISTRY & BIOLOGY (2010)
A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
Ji Luo et al.
CELL (2009)
Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1
Sarah Ehses et al.
JOURNAL OF CELL BIOLOGY (2009)
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression
Corbin E. Meacham et al.
NATURE GENETICS (2009)
Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria
Carsten Merkwirth et al.
GENES & DEVELOPMENT (2008)
Fast degradation of the auxiliary subunit of Na+/K+-ATPase in the plasma membrane of HeLa cells
Shige H. Yoshimura et al.
JOURNAL OF CELL SCIENCE (2008)
Highly parallel identification of essential genes in cancer cells
Biao Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cancer proliferation gene discovery through functional Genomics
Michael R. Schlabach et al.
SCIENCE (2008)
Profiling essential genes in human mammary cells by multiplex RNAi screening
Jose M. Silva et al.
SCIENCE (2008)
Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth
Wilhelm Schoner et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Aurilides B and C, cancer cell toxins from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula
BN Han et al.
JOURNAL OF NATURAL PRODUCTS (2006)
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
TR Brummelkamp et al.
NATURE CHEMICAL BIOLOGY (2006)
Aurilide, a cytotoxic depsipeptide from the sea hare Dolabella auricularia:: isolation, structure determination, synthesis, and biological activity
K Suenaga et al.
TETRAHEDRON (2004)
Na+/K+-ATPase as a signal transducer
ZJ Xie et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Ouabain, a steroid hormone that signals with slow calcium oscillations
O Aizman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
分享论文
