相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects
Diana Papp et al.
AUTOPHAGY (2016)
AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease
Viktor Billes et al.
JOURNAL OF HUNTINGTONS DISEASE (2016)
Development of autophagy inducers in clinical medicine
Beth Levine et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Huntingtin functions as a scaffold for selective macroautophagy
Yan-Ning Rui et al.
NATURE CELL BIOLOGY (2015)
Compromised autophagy and neurodegenerative diseases
Fiona M. Menzies et al.
NATURE REVIEWS NEUROSCIENCE (2015)
Specialized Cortex Glial Cells Accumulate Lipid Droplets in Drosophila melanogaster
Viktor Kis et al.
PLOS ONE (2015)
Deficiency of myotubularin-related protein 14 influences body weight, metabolism, and inflammation in an age-dependent manner
Yin Lv et al.
CELL AND BIOSCIENCE (2015)
Cultured cells of the blood-brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment
Nikolett Lenart et al.
FLUIDS AND BARRIERS OF THE CNS (2015)
Sucrose Esters Increase Drug Penetration, But Do Not Inhibit P-Glycoprotein in Caco-2 Intestinal Epithelial Cells
Lorand Kiss et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy
Chen-Chen Tan et al.
NEUROBIOLOGY OF AGING (2014)
Assays to monitor autophagy in Drosophila
Caroline Mauvezin et al.
METHODS (2014)
Potential function for the Huntingtin protein as a scaffold for selective autophagy
Joseph Ochaba et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Autophagosomal Syntaxin 17-dependent lysosomal degradation maintains neuronal function in Drosophila
Szabolcs Takats et al.
JOURNAL OF CELL BIOLOGY (2013)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models
Eve Hellinger et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2012)
Kinome-wide Selectivity Profiling of ATP-competitive Mammalian Target of Rapamycin (mTOR) Inhibitors and Characterization of Their Binding Kinetics
Qingsong Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Advantages and Limitations of Different p62-Based Assays for Estimating Autophagic Activity in Drosophila
Karolina Pircs et al.
PLOS ONE (2012)
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
Nadia Jaber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The ORCA program system
Frank Neese
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2012)
Autophagy and apoptosis are redundantly required for C. elegans embryogenesis
Eva Borsos et al.
AUTOPHAGY (2011)
Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy
Phillip Hundeshagen et al.
BMC BIOLOGY (2011)
The regulation of autophagy - unanswered questions
Yongqiang Chen et al.
JOURNAL OF CELL SCIENCE (2011)
Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans
Peter Erdelyi et al.
JOURNAL OF CELL SCIENCE (2011)
Zebrafish MTMR14 is required for excitation-contraction coupling, developmental motor function and the regulation of autophagy
J. J. Dowling et al.
HUMAN MOLECULAR GENETICS (2010)
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
Cristofol Vives-Bauza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
An Autophagy-Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis
Tunda Hidvegi et al.
SCIENCE (2010)
Parkin-induced mitophagy in the pathogenesis of Parkinson disease
Derek Narendra et al.
AUTOPHAGY (2009)
Control of autophagy initiation by phosphoinositide 3-phosphatase jumpy
Isabelle Vergne et al.
EMBO JOURNAL (2009)
An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation
Yu-Yun Chang et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
Shinsuke Nakagawa et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
The regulation of aging: does autophagy underlie longevity?
Tibor Vellai et al.
TRENDS IN CELL BIOLOGY (2009)
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Anne Simonsen et al.
AUTOPHAGY (2008)
The role of TOR in autophagy regulation from yeast to plants and mammals
Sandra Diaz-Troya et al.
AUTOPHAGY (2008)
A review of Parkinson's disease
C. A. Davie
BRITISH MEDICAL BULLETIN (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function
Cong Zhang et al.
NATURE MEDICINE (2008)
Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm
Eliana Romero et al.
NEURON (2008)
Autophagy and aging: keeping that old broom working
Ana Maria Cuervo
TRENDS IN GENETICS (2008)
Small molecule regulators of autophagy identified by an image-based high-throughput screen
Lihong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities
Cheng Wang et al.
JOURNAL OF NEUROSCIENCE (2007)
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
Sovan Sarkar et al.
NATURE CHEMICAL BIOLOGY (2007)
A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy
Valerie Tosch et al.
HUMAN MOLECULAR GENETICS (2006)
Autophagy in neuronal cell loss: a road to death
Krisztina Takacs-Vellai et al.
BIOESSAYS (2006)
The roles of intracellular protein-degradation pathways in neurodegeneration
David C. Rubinsztein
NATURE (2006)
Myotubularin phosphatases: policing 3-phosphoinositides
Fred L. Robinson et al.
TRENDS IN CELL BIOLOGY (2006)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
G Bjorkoy et al.
JOURNAL OF CELL BIOLOGY (2005)
Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C-elegans
K Takacs-Vellai et al.
CURRENT BIOLOGY (2005)
The molecular machinery of autophagy: unanswered questions
DJ Klionsky
JOURNAL OF CELL SCIENCE (2005)
Genetics and the specificity of the aging process
S Hekimi et al.
SCIENCE (2003)
A Drosophila model of Parkinson's disease
MB Feany et al.
NATURE (2000)