相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Potential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?
S. Baig et al.
CELL DEATH & DISEASE (2016)
Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner
Bing Yan et al.
BMC CANCER (2015)
Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response
Esther H. Lips et al.
BREAST CANCER RESEARCH (2015)
Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells
Giulia Guzzo et al.
ONCOTARGET (2014)
Targeting the Mitochondrial Electron Transport Chain Complexes for the Induction of Apoptosis and Cancer Treatment
Jakub Rohlena et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2013)
Classification of mitocans, anti-cancer drugs acting on mitochondria
Jiri Neuzil et al.
MITOCHONDRION (2013)
A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen
Dennis Ma et al.
INVESTIGATIONAL NEW DRUGS (2012)
How cancer metabolism is tuned for proliferation and vulnerable to disruption
Almut Schulze et al.
NATURE (2012)
Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells
Marco Spinazzi et al.
NATURE PROTOCOLS (2012)
Assessing mitochondrial dysfunction in cells
Martin D. Brand et al.
BIOCHEMICAL JOURNAL (2011)
Synthesis of C-1 homologues of pancratistatin and their preliminary biological evaluation
Sergey Vshyvenko et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Specific disintegration of complex II succinate: ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction
A. Lemarie et al.
CELL DEATH AND DIFFERENTIATION (2011)
Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts
Carly Griffin et al.
MOLECULAR CANCER THERAPEUTICS (2011)
被撤回的出版物: Selective killing of cancer cells by a small molecule targeting the stress response to ROS (Retracted article. See vol. 561, pg. 420, 2018)
Lakshmi Raj et al.
NATURE (2011)
Selective Cytotoxicity against Human Osteosarcoma Cells by a Novel Synthetic C-1 Analogue of 7-Deoxypancratistatin Is Potentiated by Curcumin
Dennis Ma et al.
PLOS ONE (2011)
Pancratistatin induces apoptosis in clinical leukemia samples with minimal effect on non-cancerous peripheral blood mononuclear cells
Carly Griffin et al.
CANCER CELL INTERNATIONAL (2010)
Molecular mechanisms of late apoptotic/necrotic cell clearance
I. K. H. Poon et al.
CELL DEATH AND DIFFERENTIATION (2010)
Chemoenzymatic Synthesis of Amaryllidaceae Constituents and Biological Evaluation of their C-1 Analogues. The Next Generation Synthesis of 7-Deoxypancratistatin and trans-Dihydrolycoricidine
Jonathan Collins et al.
JOURNAL OF ORGANIC CHEMISTRY (2010)
Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds
Gang Chen et al.
MITOCHONDRION (2010)
The Warburg effect and mitochondrial stability in cancer cells
Vladimir Gogvadze et al.
MOLECULAR ASPECTS OF MEDICINE (2010)
CHEMOTHERAPY Gemcitabine remains the standard of care for pancreatic cancer
Jordan Berlin et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2010)
Mitochondria and cell death: outer membrane permeabilization and beyond
Stephen W. G. Tait et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Synergy of Pancratistatin and Tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria
Peter Siedlakowski et al.
CANCER BIOLOGY & THERAPY (2008)
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
Ralph J. DeBerardinis et al.
CELL METABOLISM (2008)
Cytochrome c:: functions beyond respiration
Yong-Ling P. Ow et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Bcl-2 family proteins and cancer
K. W. Yip et al.
ONCOGENE (2008)
Complex I is the major site of mitochondrial superoxide production by paraquat
Helena M. Cocheme et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species
Yongqiang Chen et al.
JOURNAL OF CELL SCIENCE (2007)
Three-dimensional culture models of normal and malignant breast epithelial cells
Genee Y. Lee et al.
NATURE METHODS (2007)
Mitochondrial membrane permeabilization in cell death
Guido Kroemer et al.
PHYSIOLOGICAL REVIEWS (2007)
Mitocans: Mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents
Stephen J. Ralph et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2006)
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
Michael T. Lin et al.
NATURE (2006)
Molecular mechanism of 'mitocan'-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins
Jiri Neuzil et al.
FEBS LETTERS (2006)
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
Dunyaporn Trachootham et al.
CANCER CELL (2006)
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
S. Fulda et al.
ONCOGENE (2006)
The mitochondrial effects of small organic ligands of BCL-2 - Sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative
E Milanesi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells
N Kekre et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2005)
Pancratistatin: A natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis
A McLachlan et al.
APOPTOSIS (2005)
Opinion - The role of apoptosis in cancer development and treatment response
JM Brown et al.
NATURE REVIEWS CANCER (2005)
Microtubules as a target for anticancer drugs
MA Jordan et al.
NATURE REVIEWS CANCER (2004)
Many cuts to ruin: a comprehensive update of caspase substrates
U Fischer et al.
CELL DEATH AND DIFFERENTIATION (2003)
Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms
CA Belmokhtar et al.
ONCOGENE (2001)
A structural view of mitochondria-mediated apoptosis
YG Shi
NATURE STRUCTURAL BIOLOGY (2001)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes ΔΨm loss, caspase-9 activity, and apoptosis in Jurkat cells
S Gamen et al.
EXPERIMENTAL CELL RESEARCH (2000)
分享论文
