相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading
Marija Iljina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Oligomers of Parkinson's Disease-Related α-Synuclein Mutants Have Similar Structures but Distinctive Membrane Permeabilization Properties
Anja N. D. Stefanovic et al.
BIOCHEMISTRY (2015)
Dimerization propensities of Synucleins are not predictive for Synuclein aggregation
Katrin Eckermann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis
Zhengjian Lv et al.
BIOPHYSICAL JOURNAL (2015)
Lewy Bodies: A Spectator or Salient Killer?
Jeswinder Sian-Huelsmann et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2015)
Gateway-compatible vectors for high-throughput protein expression in pro- and eukaryotic cell-free systems
Dejan Gagoski et al.
JOURNAL OF BIOTECHNOLOGY (2015)
Cuminaldehyde as the Major Component of Cuminum cyminum, a Natural Aldehyde with Inhibitory Effect on Alpha-Synuclein Fibrillation and Cytotoxicity
Dina Morshedi et al.
JOURNAL OF FOOD SCIENCE (2015)
Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils
Wenhua Chu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Alpha-synuclein oligomers and fibrils originate in two distinct conformer pools: a small angle X-ray scattering and ensemble optimisation modelling study
Cyril C. Curtain et al.
MOLECULAR BIOSYSTEMS (2015)
Human Hsp70 Disaggregase Reverses Parkinson's-Linked α-Synuclein Amyloid Fibrils
Xuechao Gao et al.
MOLECULAR CELL (2015)
Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation
Aoife P. Kiely et al.
MOLECULAR NEURODEGENERATION (2015)
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
W. Peelaerts et al.
NATURE (2015)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
Serene W. Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Propagation of prions causing synucleinopathies in cultured cells
Amanda L. Woerman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
Stanley B. Prusiner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants
Laura Tosatto et al.
SCIENTIFIC REPORTS (2015)
Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism
Valerie R. Osterberg et al.
CELL REPORTS (2015)
The Synaptic Function of α-Synuclein
Jacqueline Burre
JOURNAL OF PARKINSONS DISEASE (2015)
The N-Terminal Residues 43 to 60 Form the Interface for Dopamine Mediated α-Synuclein Dimerisation
Su Ling Leong et al.
PLOS ONE (2015)
Co-existence of Two Different α-Synuclein Oligomers with Different Core Structures Determined by Hydrogen/Deuterium Exchange Mass Spectrometry
Wojciech Paslawski et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
High Stability and Cooperative Unfolding of α-Synuclein Oligomers
Wojciech Paslawski et al.
BIOCHEMISTRY (2014)
Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells
N. Plotegher et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Defined α-synuclein prion-like molecular assemblies spreading in cell culture
Suzana Aulic et al.
BMC NEUROSCIENCE (2014)
Prion-like Mechanisms in the Pathogenesis of Tauopathies and Synucleinopathies
Michel Goedert et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2014)
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells
Mohamed-Bilal Fares et al.
HUMAN MOLECULAR GENETICS (2014)
The H50Q Mutation Enhances α-Synuclein Aggregation, Secretion, and Toxicity
Ossama Khalaf et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Early oligomerization stages for the non-amyloid component of α-synuclein amyloid
Cindie Eugene et al.
JOURNAL OF CHEMICAL PHYSICS (2014)
Divergent effects of the H5OQ and G51D SNCA mutations on the aggregation of α-synuclein
Nicola J. Rutherford et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Rapid Mapping of Interactions between Human SNX-BAR Proteins Measured In Vitro by AlphaScreen and Single-molecule Spectroscopy
Emma Sierecki et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Diverse Metastable Structures Formed by Small Oligomers of α-Synuclein Probed by Force Spectroscopy
Krishna Neupane et al.
PLOS ONE (2014)
In vitro aggregation assays for the characterization of α-synuclein prion-like properties
Joanna Narkiewicz et al.
PRION (2014)
Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity
Nicoletta Plotegher et al.
QUARTERLY REVIEWS OF BIOPHYSICS (2014)
Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
Diana F. Lazaro et al.
PLOS GENETICS (2014)
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae
Yann Gambin et al.
ELIFE (2014)
α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?
Aoife P. Kiely et al.
ACTA NEUROPATHOLOGICA (2013)
G51D α-Synuclein mutation causes a novel Parkinsonian-pyramidal syndrome
Suzanne Lesage et al.
ANNALS OF NEUROLOGY (2013)
The Parkinson's Disease-Associated H50Q Mutation Accelerates α-Synuclein Aggregation in Vitro
Dhiman Ghosh et al.
BIOCHEMISTRY (2013)
α-Synuclein: The Long Distance Runner
Sonia George et al.
BRAIN PATHOLOGY (2013)
Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
Jing L. Guo et al.
CELL (2013)
A flash in the pan: Dissecting dynamic amyloid intermediates using fluorescence
Abhinav Nath et al.
FEBS LETTERS (2013)
Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
Silke Appel-Cresswell et al.
MOVEMENT DISORDERS (2013)
100 years of Lewy pathology
Michel Goedert et al.
NATURE REVIEWS NEUROLOGY (2013)
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
David J. Irwin et al.
NATURE REVIEWS NEUROSCIENCE (2013)
The many faces of alpha-synuclein: from structure and toxicity to therapeutic target
Hilal A. Lashuel et al.
NATURE REVIEWS NEUROSCIENCE (2013)
A NOVEL α-SYNUCLEIN MISSENSE MUTATION IN PARKINSON DISEASE
Christos Proukakis et al.
NEUROLOGY (2013)
Update on novel familial forms of Parkinson's disease and multiple system atrophy
Shinsuke Fujioka et al.
PARKINSONISM & RELATED DISORDERS (2013)
Site-Specific Perturbations of Alpha-Synuclein Fibril Structure by the Parkinson's Disease Associated Mutations A53T and E46K
Luisel R. Lemkau et al.
PLOS ONE (2013)
Structural and functional characterization of two alpha-synuclein strains
Luc Bousset et al.
NATURE COMMUNICATIONS (2013)
A cell-free approach to accelerate the study of protein-protein interactions in vitro
E. Sierecki et al.
INTERFACE FOCUS (2013)
Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure
Maria Soledad Celej et al.
BIOCHEMICAL JOURNAL (2012)
Mutant Protein A30P α-Synuclein Adopts Wild-type Fibril Structure, Despite Slower Fibrillation Kinetics
Luisel R. Lemkau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A deadly spread: cellular mechanisms of α-synuclein transfer
J. A. Steiner et al.
CELL DEATH AND DIFFERENTIATION (2011)
Structured Regions of α-Synuclein Fibrils Include the Early-Onset Parkinson's Disease Mutation Sites
Gemma Comellas et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Leishmania cell-free protein expression system
Oleksiy Kovtun et al.
METHODS (2011)
Pre-Fibrillar α-Synuclein Mutants Cause Parkinson's Disease-Like Non-Motor Symptoms in Drosophila
Madhu Babu Gajula Balija et al.
PLOS ONE (2011)
In vivo demonstration that α-synuclein oligomers are toxic
Beate Winner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Towards Multiparametric Fluorescent Imaging of Amyloid Formation: Studies of a YFP Model of α-Synuclein Aggregation
Tjakko J. van Ham et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Structural and thermodynamic analysis of the GFP:GFP-nanobody complex
Marta H. Kubala et al.
PROTEIN SCIENCE (2010)
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
Jacqueline Burre et al.
SCIENCE (2010)
Species-independent translational leaders facilitate cell-free expression
Sergei Mureev et al.
NATURE BIOTECHNOLOGY (2009)
Guiding protein aggregation with macromolecular crowding
Larissa A. Munishkina et al.
BIOCHEMISTRY (2008)
Mapping the number of molecules and brightness in the laser scanning microscope
Michelle A. Digman et al.
BIOPHYSICAL JOURNAL (2008)
Selective chemical labeling of proteins with small fluorescent molecules based on metal-chelation methodology
Nobuaki Soh
SENSORS (2008)
The impact of the E46K mutation on the properties of α-synuclein in its monomeric and oligomeric states
Ross A. Fredenburg et al.
BIOCHEMISTRY (2007)
Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from α-synuclein mutants
Martijn E. van Raaij et al.
BIOPHYSICAL JOURNAL (2006)
The aggregation and fibrillation of α-synuclein
Anthony L. Fink
ACCOUNTS OF CHEMICAL RESEARCH (2006)
The alpha-synuclein mutation E46K promotes aggregation in cultured cells
N Pandey et al.
EXPERIMENTAL NEUROLOGY (2006)
Engineering and characterization of a superfolder green fluorescent protein
JD Pedelacq et al.
NATURE BIOTECHNOLOGY (2006)
Structural determinants of PLD2 inhibition by α-synuclein
JE Payton et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
Accelerated α-synuclein fibrillation in crowded milieu
VN Uversky et al.
FEBS LETTERS (2002)
Molecular crowding accelerates fibrillization of α-synuclein:: Could an increase in the cytoplasmic protein concentration induce Parkinson's disease?
MD Shtilerman et al.
BIOCHEMISTRY (2002)
Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein
J Li et al.
BIOCHEMISTRY (2001)
Fibrils formed in vitro from α-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid
KA Conway et al.
BIOCHEMISTRY (2000)
Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease:: Implications for pathogenesis and therapy
KA Conway et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
