相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Helix Nucleation by the Smallest Known α-Helix in Water
Huy N. Hoang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
An In-tether Chiral Center Modulates the Helicity, Cell Permeability, and Target Binding Affinity of a Peptide
Kuan Hu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Stapled Peptides with -Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction
Thomas E. Speltz et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Small molecules, big targets: drug discovery faces the protein-protein interaction challenge
Duncan E. Scott et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Systematic Targeting of Protein-Protein Interactions
Ashley E. Modell et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
Stapling of unprotected helical peptides via photoinduced intramolecular thiol-yne hydrothiolation
Yuan Tian et al.
CHEMICAL SCIENCE (2016)
α-Peptide-Oligourea Chimeras: Stabilization of Short α-Helices by Non-Peptide Helical Foldamers
Juliette Fremaux et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Comparative α-Helicity of Cyclic Pentapeptides in Water
Aline D. de Araujo et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality
Michelle R. Arkin et al.
CHEMISTRY & BIOLOGY (2014)
Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress
Loren D. Walensky et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Influence of α-methylation in constructing stapled peptides with olefin metathesis
Qingzhou Zhang et al.
TETRAHEDRON (2014)
Functionalised staple linkages for modulating the cellular activity of stapled peptides
Yu Heng Lau et al.
CHEMICAL SCIENCE (2014)
Getting in Shape: Controlling Peptide Bioactivity and Bioavailability Using Conformational Constraints
Jonathan E. Bock et al.
ACS CHEMICAL BIOLOGY (2013)
The Future of Peptide-based Drugs
David J. Craik et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2013)
A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling
Alexander M. Spokoyny et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery?
Philipp Thiel et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Biaryl-Bridged Macrocyclic Peptides: Conformational Constraint via Carbogenic Fusion of Natural Amino Acid Side Chains
Falco-Magnus Meyer et al.
JOURNAL OF ORGANIC CHEMISTRY (2012)
Protein-protein interaction inhibitors get into the groove
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2012)
Achieving cell penetration with distance-matching cysteine cross-linkers: a facile route to cell-permeable peptide dual inhibitors of Mdm2/Mdmx
Avinash Muppidi et al.
CHEMICAL COMMUNICATIONS (2011)
Stabilized helical peptides: overview of the technologies and therapeutic promises
Karine Estieu-Gionnet et al.
EXPERT OPINION ON DRUG DISCOVERY (2011)
Design and Structure of Stapled Peptides Binding to Estrogen Receptors
Chris Phillips et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Systematic Analysis of Helical Protein Interfaces Reveals Targets for Synthetic Inhibitors
Andrea L. Jochim et al.
ACS CHEMICAL BIOLOGY (2010)
On-resin peptide macrocyclization using thiol-ene click chemistry
Alex A. Aimetti et al.
CHEMICAL COMMUNICATIONS (2010)
Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions
Aleksandr V. Marenich et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
All-Atom Model for Stabilization of α-Helical Structure in Peptides by Hydrocarbon Staples
Peter S. Kutchukian et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Assessment of helical interfaces in protein-protein interactions
Andrea L. Jochim et al.
MOLECULAR BIOSYSTEMS (2009)
Atomic structure of a short α-helix stabilized by a main chain hydrogen-bond surrogate
Jie Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Facile and E-selective intramolecular ring-closing metathesis reactions in 310-helical peptides:: A 3D structural study
Amie K. Boal et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Comparison of multiple amber force fields and development of improved protein backbone parameters
Viktor Hornak et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
Drugs targeting protein-protein interactions
Patrick Chene
CHEMMEDCHEM (2006)
Single turn peptide alpha helices with exceptional stability in water
NE Shepherd et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Strategies for targeting protein-protein interactions with synthetic agents
H Yin et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
MR Arkin et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Exploring protein native states and large-scale conformational changes with a modified generalized born model
A Onufriev et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Aib-based peptide backbone as scaffolds for helical peptide mimics
R Banerjee et al.
JOURNAL OF PEPTIDE RESEARCH (2002)
Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53
C García-Echeverría et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides
CE Schafmeister et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
分享论文
