相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
Andreas C. Woerner et al.
SCIENCE (2016)
Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation
Saskia Polling et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Proteins with Intrinsically Disordered Domains Are Preferentially Recruited to Polyglutamine Aggregates
Maggie P. Wear et al.
PLOS ONE (2015)
Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation
Saskia Polling et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
A protein polymerization cascade mediates toxicity of non-pathological human huntingtin in yeast
Genrikh V. Serpionov et al.
SCIENTIFIC REPORTS (2015)
Cytotoxicity of Mutant Huntingtin Fragment in Yeast Can Be Modulated by the Expression Level of Wild Type Huntingtin Fragment
Aliabbas Ahmedbhai Saleh et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Effect of Helical Flanking Sequences on the Morphology of Polyglutamine-Containing Fibrils
Bashkim Kokona et al.
BIOCHEMISTRY (2014)
Architecture of Polyglutamine-containing Fibrils from Time-resolved Fluorescence Decay
Christoph Roethlein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Only a subset of the PAB1-mRNP proteome is present in mRNA translation complexes
Chongxu Zhang et al.
PROTEIN SCIENCE (2014)
Monomeric, Oligomeric and Polymeric Proteins in Huntington Disease and Other Diseases of Polyglutamine Expansion
Guylaine Hoffner et al.
BRAIN SCIENCES (2014)
PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone
Sae-Hun Park et al.
CELL (2013)
A Platform to View Huntingtin Exon 1 Aggregation Flux in the Cell Reveals Divergent Influences from Chaperones hsp40 and hsp70
Angelique R. Ormsby et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The role of amyloidogenic protein oligomerization in neurodegenerative disease
Gregor P. Lotz et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting
Ayala Shiber et al.
MOLECULAR BIOLOGY OF THE CELL (2013)
The RRM1 domain of the poly(A)-binding protein from Saccharomyces cerevisiae is critical to control of mRNA deadenylation
Chongxu Zhang et al.
MOLECULAR GENETICS AND GENOMICS (2013)
A network of genes connects polyglutamine toxicity to ploidy control in yeast
Christoph J. O. Kaiser et al.
NATURE COMMUNICATIONS (2013)
Pharmacological Tuning of Heat Shock Protein 70 Modulates Polyglutamine Toxicity and Aggregation
Sidhartha M. Chafekar et al.
ACS CHEMICAL BIOLOGY (2012)
Aggregation of PolyQ Proteins Is Increased upon Yeast Aging and Affected by Sir2 and Hsf1: Novel Quantitative Biochemical and Microscopic Assays
Aviv Cohen et al.
PLOS ONE (2012)
Use of the novel technique of analytical ultracentrifugation with fluorescence detection system identifies a 77S monosomal translation complex
Xin Wang et al.
PROTEIN SCIENCE (2012)
Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast
He Gong et al.
PLOS GENETICS (2012)
Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation
M. Alba Sorolla et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
Ordered Assembly of Heat Shock Proteins, Hsp26, Hsp70 Hsp90, and Hsp104, on Expanded Polyglutamine Fragments Revealed by Chemical Probes
Gladis M. Walter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Monitoring polyglutamine toxicity in yeast
Martin L. Duennwald
METHODS (2011)
Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool
Maya A. Olshina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Chaperone networks: Tipping the balance in protein folding diseases
Cindy Voisine et al.
NEUROBIOLOGY OF DISEASE (2010)
Countering amyloid polymorphism and drug resistance with minimal drug cocktails
Martin L. Duennwald et al.
PRION (2010)
NUTS and BOLTS: Applications of fluorescence-detected sedimentation
Rachel R. Kroe et al.
ANALYTICAL BIOCHEMISTRY (2009)
Protein aggregation and neurodegeneration: Clues from a yeast model of Huntington's disease
N. Bocharova et al.
BIOCHEMISTRY-MOSCOW (2009)
Amyloid deposits Protection against toxic protein species?
Sebastian Treusch et al.
CELL CYCLE (2009)
Modulation of polyglutamine inclusion formation by the Hsp70 chaperone machine
M. A. Rujano et al.
EXPERIMENTAL CELL RESEARCH (2007)
Characterization of Proteins Associated with Polyglutamine Aggregates A Novel Approach Towards Isolation of Aggregates from Protein Conformation Disorders
Yan Wang et al.
PRION (2007)
Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models
Dagmar E. Ehrnhoefer et al.
HUMAN MOLECULAR GENETICS (2006)
Flanking sequences profoundly alter polyglutamine toxicity in yeast
Martin L. Duennwald et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A network of protein interactions determines polyglutamine toxicity
Martin L. Duennwald et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
P Venkatraman et al.
MOLECULAR CELL (2004)
Fluorescence detection for the XLI analytical ultracentrifuge
IK MacGregor et al.
BIOPHYSICAL CHEMISTRY (2004)
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M Arrasate et al.
NATURE (2004)
Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis
AB Meriin et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1
AB Meriin et al.
JOURNAL OF CELL BIOLOGY (2002)
The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin
W Auerbach et al.
HUMAN MOLECULAR GENETICS (2001)
Mechanism of prion loss after Hsp104 inactivation in yeast
RD Wegrzyn et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
JS Steffan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins
S Krobitsch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)