4.7 Article

Multiple discrete soluble aggregates influence polyglutamine toxicity in a Huntington's disease model system

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA

Andreas C. Woerner et al.

SCIENCE (2016)

Article Biochemistry & Molecular Biology

Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation

Saskia Polling et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation

Saskia Polling et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)

Article Multidisciplinary Sciences

A protein polymerization cascade mediates toxicity of non-pathological human huntingtin in yeast

Genrikh V. Serpionov et al.

SCIENTIFIC REPORTS (2015)

Article Biochemistry & Molecular Biology

Cytotoxicity of Mutant Huntingtin Fragment in Yeast Can Be Modulated by the Expression Level of Wild Type Huntingtin Fragment

Aliabbas Ahmedbhai Saleh et al.

ACS CHEMICAL NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Effect of Helical Flanking Sequences on the Morphology of Polyglutamine-Containing Fibrils

Bashkim Kokona et al.

BIOCHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Architecture of Polyglutamine-containing Fibrils from Time-resolved Fluorescence Decay

Christoph Roethlein et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Only a subset of the PAB1-mRNP proteome is present in mRNA translation complexes

Chongxu Zhang et al.

PROTEIN SCIENCE (2014)

Article Biochemistry & Molecular Biology

A Platform to View Huntingtin Exon 1 Aggregation Flux in the Cell Reveals Divergent Influences from Chaperones hsp40 and hsp70

Angelique R. Ormsby et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Genetics & Heredity

The role of amyloidogenic protein oligomerization in neurodegenerative disease

Gregor P. Lotz et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2013)

Article Biochemistry & Molecular Biology

The RRM1 domain of the poly(A)-binding protein from Saccharomyces cerevisiae is critical to control of mRNA deadenylation

Chongxu Zhang et al.

MOLECULAR GENETICS AND GENOMICS (2013)

Article Multidisciplinary Sciences

A network of genes connects polyglutamine toxicity to ploidy control in yeast

Christoph J. O. Kaiser et al.

NATURE COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

Pharmacological Tuning of Heat Shock Protein 70 Modulates Polyglutamine Toxicity and Aggregation

Sidhartha M. Chafekar et al.

ACS CHEMICAL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation

M. Alba Sorolla et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)

Article Biochemistry & Molecular Biology

Ordered Assembly of Heat Shock Proteins, Hsp26, Hsp70 Hsp90, and Hsp104, on Expanded Polyglutamine Fragments Revealed by Chemical Probes

Gladis M. Walter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemical Research Methods

Monitoring polyglutamine toxicity in yeast

Martin L. Duennwald

METHODS (2011)

Article Biochemistry & Molecular Biology

Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool

Maya A. Olshina et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Neurosciences

Chaperone networks: Tipping the balance in protein folding diseases

Cindy Voisine et al.

NEUROBIOLOGY OF DISEASE (2010)

Article Biochemistry & Molecular Biology

Countering amyloid polymorphism and drug resistance with minimal drug cocktails

Martin L. Duennwald et al.

Article Biochemical Research Methods

NUTS and BOLTS: Applications of fluorescence-detected sedimentation

Rachel R. Kroe et al.

ANALYTICAL BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Protein aggregation and neurodegeneration: Clues from a yeast model of Huntington's disease

N. Bocharova et al.

BIOCHEMISTRY-MOSCOW (2009)

Article Cell Biology

Amyloid deposits Protection against toxic protein species?

Sebastian Treusch et al.

CELL CYCLE (2009)

Article Oncology

Modulation of polyglutamine inclusion formation by the Hsp70 chaperone machine

M. A. Rujano et al.

EXPERIMENTAL CELL RESEARCH (2007)

Article Multidisciplinary Sciences

Flanking sequences profoundly alter polyglutamine toxicity in yeast

Martin L. Duennwald et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

A network of protein interactions determines polyglutamine toxicity

Martin L. Duennwald et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Fluorescence detection for the XLI analytical ultracentrifuge

IK MacGregor et al.

BIOPHYSICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis

AB Meriin et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin

W Auerbach et al.

HUMAN MOLECULAR GENETICS (2001)

Article Biochemistry & Molecular Biology

Mechanism of prion loss after Hsp104 inactivation in yeast

RD Wegrzyn et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)

Article Multidisciplinary Sciences

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

JS Steffan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Multidisciplinary Sciences

Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

S Krobitsch et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)