相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function
Carla Garza-Lombo et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines
Caterina M. Lombardo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
Raphael Rodriguez et al.
NATURE CHEMICAL BIOLOGY (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response
Minna Heikkila et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Antisense HIF-1α prevents acquired tumor resistance to angiostatin gene therapy
X. Sun et al.
CANCER GENE THERAPY (2010)
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
G. L. Semenza
ONCOGENE (2010)
Marked Activity of Irinotecan and Rapamycin Combination toward Colon Cancer Cells In vivo and In vitro Is Mediated through Cooperative Modulation of the Mammalian Target of Rapamycin/Hypoxia-Inducible Factor-1α Axis
Erwan Pencreach et al.
CLINICAL CANCER RESEARCH (2009)
G-quadruplex nucleic acids as therapeutic targets
Shankar Balasubramanian et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
Targeting the hypoxia-inducible factor (HIF) pathway in cancer
Evon Poon et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2009)
Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1
Gregg L. Semenza
PHYSIOLOGY (2009)
Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
KangAe Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors
Michael L. Nickerson et al.
CLINICAL CANCER RESEARCH (2008)
HYPOXIA AND METABOLISM SERIES - TIMELINE The impact of O2 availability on human cancer
Jessica A. Bertout et al.
NATURE REVIEWS CANCER (2008)
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
Dai Fukumura et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1
K. M. Sutton et al.
ONCOGENE (2007)
RACK1 competes with HSP90 for binding to HIF-1α and is required for O2-independent and HSP90 inhibitor-induced degradation of HIF-1α
Ye V. Liu et al.
MOLECULAR CELL (2007)
PML inhibits HIF-1α translation and neoangiogenesis through repression of mTOR
Rosa Bernardi et al.
NATURE (2006)
Role of hypoxia-inducible factor (HIF)-1α-versus HIF-2α in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-1, or loss of von Hippel-Lindau function:: Implications for targeting the HIF pathway
Veronica A. Carroll et al.
CANCER RESEARCH (2006)
Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer
RE Banks et al.
CANCER RESEARCH (2006)
Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1α promoter
R De Armond et al.
BIOCHEMISTRY (2005)
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
Q Xu et al.
ONCOGENE (2005)
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
RR Raval et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma:: results from the Netherlands cohort study -: art. no. 57
KP van Houwelingen et al.
BMC CANCER (2005)
Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
CJ Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Somatic von Hippel-Lindau disease gene mutation in clear-cell renal carcinomas associated with end-stage renal disease/acquired cystic disease of the kidney
M Yoshida et al.
GENES CHROMOSOMES & CANCER (2002)
Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1α-degradative pathway
JS Isaacs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A new mathematical model for relative quantification in real-time RT-PCR
MW Pfaffl
NUCLEIC ACIDS RESEARCH (2001)
Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function
M Krieg et al.
ONCOGENE (2000)
Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI3K pathway
KB Sandau et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Activation of HIF1α ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
T Kamura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
ME Cockman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein
M Ohh et al.
NATURE CELL BIOLOGY (2000)
分享论文
