4.7 Article

SRT1720 improves survival and healthspan of obese mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Endocrinology & Metabolism

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

Takeshi Yoshizaki et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)

Article Biochemical Research Methods

A high-throughput respirometric assay for mitochondrial biogenesis and toxicity

Craig C. Beeson et al.

ANALYTICAL BIOCHEMISTRY (2010)

Article Biochemistry & Molecular Biology

SIRT1 Activation by Small Molecules KINETIC AND BIOPHYSICAL EVIDENCE FOR DIRECT INTERACTION OF ENZYME AND ACTIVATOR

Han Dai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

Michelle Pacholec et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Medicine, Research & Experimental

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

Carlos Escande et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Medicine, Research & Experimental

Sirt1 activation protects the mouse renal medulla from oxidative injury

Wenjuan He et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Pharmacology & Pharmacy

SRT1720 Induces Mitochondrial Biogenesis and Rescues Mitochondrial Function after Oxidant Injury in Renal Proximal Tubule Cells

Jason A. Funk et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Article Endocrinology & Metabolism

Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice

Yu Yamazaki et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)

Article Mathematical & Computational Biology

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

Jesse J. Smith et al.

BMC SYSTEMS BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity

Dirk Beher et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2009)

Article Biochemistry & Molecular Biology

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

Przemyslaw Wareski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

Takeshi Yoshizaki et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Cell Biology

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

Alexander S. Banks et al.

CELL METABOLISM (2008)

Review Biotechnology & Applied Microbiology

Sirtuins - novel therapeutic targets to treat age-associated diseases

Siva Lavu et al.

NATURE REVIEWS DRUG DISCOVERY (2008)

Review Nutrition & Dietetics

Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases

Mitchell D. Knutson et al.

NUTRITION REVIEWS (2008)

Article Multidisciplinary Sciences

The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1α

Agnes Coste et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Sirt1 protects against high-fat diet-induced metabolic damage

Paul T. Pfluger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Physiology

Sarcopenic obesity and inflammation in the InCHIANTI study

Matthew A. Schrager et al.

JOURNAL OF APPLIED PHYSIOLOGY (2007)

Article Multidisciplinary Sciences

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur et al.

NATURE (2006)

Article Multidisciplinary Sciences

Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

G López-Lluch et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Biotechnology & Applied Microbiology

Therapeutic potential of resveratrol: the in vivo evidence

Joseph A. Baur et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Biochemistry & Molecular Biology

Mechanism of human SIRT1 activation by resveratrol

MT Borra et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Substrate-specific activation of sirtuins by resveratrol

M Kaeberlein et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Geriatrics & Gerontology

The effect of aging and caloric restriction on mitochondrial protein density and oxygen consumption

AJ Lambert et al.

EXPERIMENTAL GERONTOLOGY (2004)

Article Multidisciplinary Sciences

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

HL Cheng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

KT Howitz et al.

NATURE (2003)

Article Biochemistry & Molecular Biology

Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression

T Takata et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Article Biochemistry & Molecular Biology

Mitochondrially mediated synergistic cell killing by bile acids

AP Rolo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2003)

Article Multidisciplinary Sciences

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

HA Tissenbaum et al.

NATURE (2001)