相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver
Yu Li et al.
FASEB JOURNAL (2011)
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
Takeshi Yoshizaki et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
A high-throughput respirometric assay for mitochondrial biogenesis and toxicity
Craig C. Beeson et al.
ANALYTICAL BIOCHEMISTRY (2010)
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
Amy K. Walker et al.
GENES & DEVELOPMENT (2010)
SIRT1 Activation by Small Molecules KINETIC AND BIOPHYSICAL EVIDENCE FOR DIRECT INTERACTION OF ENZYME AND ACTIVATOR
Han Dai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
Michelle Pacholec et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice
Carlos Escande et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Sirt1 activation protects the mouse renal medulla from oxidative injury
Wenjuan He et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
SRT1720 Induces Mitochondrial Biogenesis and Rescues Mitochondrial Function after Oxidant Injury in Renal Proximal Tubule Cells
Jason A. Funk et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants
Sang-Kyu Park et al.
AGING CELL (2009)
Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice
Yu Yamazaki et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
Jesse J. Smith et al.
BMC SYSTEMS BIOLOGY (2009)
Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity
Dirk Beher et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2009)
PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons
Przemyslaw Wareski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes
Takeshi Yoshizaki et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response
Rozalyn M. Anderson et al.
AGING CELL (2008)
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
Kevin J. Pearson et al.
CELL METABOLISM (2008)
SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
Alexander S. Banks et al.
CELL METABOLISM (2008)
Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-induced Metabolic Disorders by Enhancing Fat Oxidation
Jerome N. Feige et al.
CELL METABOLISM (2008)
Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart
J. L. Barger et al.
EXPERIMENTAL GERONTOLOGY (2008)
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
Yi Liu et al.
NATURE (2008)
Sirtuins - novel therapeutic targets to treat age-associated diseases
Siva Lavu et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases
Mitchell D. Knutson et al.
NUTRITION REVIEWS (2008)
A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
Jamie L. Barger et al.
PLOS ONE (2008)
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1α
Agnes Coste et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Sirt1 protects against high-fat diet-induced metabolic damage
Paul T. Pfluger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne et al.
NATURE (2007)
Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging
William R. Swindell
BMC GENOMICS (2007)
Sarcopenic obesity and inflammation in the InCHIANTI study
Matthew A. Schrager et al.
JOURNAL OF APPLIED PHYSIOLOGY (2007)
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
Marie Lagouge et al.
CELL (2006)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
G López-Lluch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Therapeutic potential of resveratrol: the in vivo evidence
Joseph A. Baur et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Mechanism of human SIRT1 activation by resveratrol
MT Borra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Substrate-specific activation of sirtuins by resveratrol
M Kaeberlein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
The effect of aging and caloric restriction on mitochondrial protein density and oxygen consumption
AJ Lambert et al.
EXPERIMENTAL GERONTOLOGY (2004)
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
HL Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression
T Takata et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Mitochondrially mediated synergistic cell killing by bile acids
AP Rolo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2003)
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
HA Tissenbaum et al.
NATURE (2001)
Bile acids affect liver mitochondrial bioenergetics: Possible relevance for cholestasis therapy
AP Rolo et al.
TOXICOLOGICAL SCIENCES (2000)