期刊
RSC ADVANCES
卷 8, 期 51, 页码 29189-29200出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ra05278f
关键词
-
资金
- National Institute for Materials Science (NIMS)
- JSPS KAKENHI [26282151]
- Grants-in-Aid for Scientific Research [26282151] Funding Source: KAKEN
In this study, the surface of magnesium metal was electrochemically engineered for enhanced biocompatibility and controlled degradation in body fluid. Firstly, a plasma electrolytic oxidation (PEO) coating was formed on magnesium, followed by electrochemical deposition of calcium phosphate (CaP) using an unconventional electrolyte. Cytocompatibility tests using L929 cells revealed that the PEO-CaP coating significantly improved the biocompatibility of magnesium. In vitro electrochemical degradation experiments in simulated body fluid (SBF) showed that the PEO-CaP coating improved the degradation resistance of magnesium significantly. The corrosion current density (i(corr)) of the PEO-CaP coated magnesium was approximate to 99% and approximate to 97% lower than that of bare magnesium and the PEO-only coated magnesium, respectively. Similarly, electrochemical impedance spectroscopy (EIS) results showed that the polarisation resistance (R-P) of the PEO-CaP coated magnesium was one-order of magnitude higher as compared to the PEO-only coated magnesium and two-orders of magnitude higher than the bare magnesium, after 72 h immersion in SBF. Scanning electron microscopy (SEM) analysis revealed no localized degradation in the PEO-CaP coated magnesium. The study demonstrated that the PEO-CaP coating is a promising combination for enhancing the biocompatibility and reducing the degradation of magnesium for potential biodegradable implant applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据