期刊
RSC ADVANCES
卷 4, 期 26, 页码 13430-13433出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra01442a
关键词
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资金
- Christian Doppler Research Society (CDG)
A method for the direct lithiation of terminal alkynes and heterocycles with subsequent carboxylation in a continuous flow format was developed. This method provides carboxylic acids at ambient conditions within less than five seconds with only little excess of the organometallic base and CO2.
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