4.6 Article

Iodine-PPh3-mediated C3-sulfenylation of indoles with sodium sulfinates

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RSC ADVANCES
卷 4, 期 36, 页码 18933-18938

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra02607a

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资金

  1. Thailand Research Fund [TRF-DBG5480017]
  2. Center of Excellence for Innovation in Chemistry (PERCH-CIC)
  3. Office of the Higher Education Commission, Mahidol University under the National Research Universities Initiative
  4. Development and Promotion of Science and Technology Talent Project (DPST)
  5. Institute for the Promotion of Teaching Science and Technology

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3-(Alkylsulfanyl)- and 3-(arylsulfanyl)indoles were efficiently prepared by the reaction of indoles with sodium sulfinates mediated by iodine-PPh3 in ethanol. The salient features of the present protocol are simplicity, high efficiency, non-anhydrous conditions, environmentally friendly reagents and solvent, and short reaction time.

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