期刊
RSC ADVANCES
卷 4, 期 71, 页码 37889-37899出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra06239f
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资金
- DST, New Delhi [SR/FT/CS-042/2009]
- IIT Patna
- CSIR
- UGC
A clean, efficient and catalyst-free multicomponent domino reaction of arylglyoxals, cyclic 1,3-dicarbonyls and thioamides in aqueous media under microwave conditions is reported. A wide variety of trisubstituted thiazoles can be synthesized in good to very good yields using this green protocol. The salient features of this methodology are: catalyst-free reaction, water as reaction medium, short reaction time, good yields, use of microwave heating, and no harmful by-products.
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