Copper nanoparticle-catalyzed borylation of alkyl bromides with an organodiboron compound

Borylation of primary and secondary alkyl bromides with bis(pinaco-lato)diboron was carried out in the presence of commercially available copper nanoparticles as catalysts. The reaction went to completion in the absence of phosphines at room temperature. The catalytic system showed high activity, broad substrate scope, and good functional group tolerance.