期刊
RSC ADVANCES
卷 4, 期 3, 页码 1116-1119出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra44576c
关键词
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资金
- US Department of Energy
- Faculty Research Participation Program at the US Army Natick Soldier Research, Development and Engineering Centre (NSRDEC)
- University of Massachusetts Lowell
- Graduate Student Association at University of Massachusetts Lowell
Two water dispersible and two-photon (TP) active polymer nanoparticles were synthesized from poly[2-(3-thienyl) ethanol n-butoxy carbonyl methyl-urethane] and poly(3,3'''-didodecyl quarter thiophene) polymers using a simple miniemulsion technique. Strong TP fluorescence was observed from each of these nanoparticles using a femtosecond laser operated at 800 nm. Interestingly, these polymeric nanoparticles were found to be non-toxic in dose dependent cell viability studies for 24 h nanoparticle incubation time period. TP microscopic imaging and Z-stacking confirmed cellular internalization of TP active nanoparticles by human macrophage THP-1 cells. These fluorescent polymer nanoparticles could be suitable candidates for in vitro TP bioimaging.
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