Sporormiellin A, the first tetrahydrofuran-fused furochromone with an unprecedented tetracyclic skeleton from Sporormiella minima

Sporormiellin A (1), the first tetrahydrofuran-fused furochromone with an unprecedented tetracyclic skeleton, has been obtained from the fungal strain Sporormiella minima. The structure with absolute configuration was elucidated by NMR data, X-ray crystallography, and quantum chemical ECD calculations.