期刊
RSC ADVANCES
卷 3, 期 38, 页码 16962-16966出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra42621a
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资金
- National High Technology Research and Development Program (863'' Program) of China [2012AA101405]
- Special Fund for Agro-scientific Research in the Public Interest of China [200903056]
- National Natural Science Foundation of China [31071860]
A fluorescence quenching result was obtained when an FAM-labelled G-rich oligonucleotide T30695 was treated with Pb2+, owing to the formation of a lead(II)-stabilized G-quadruplex. Based on this phenomenon a selective fluorescent assay for lead(II) detection with a limit of detection of 0.77 ppb and a detection range from 0 to 200 ppb was constructed.
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