期刊
RSC ADVANCES
卷 3, 期 43, 页码 20883-20890出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra43407a
关键词
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资金
- Science and Engineering Research Board (SERB)
- Department of Science and Technology, India [CS-045/2013]
A facile and efficient protocol for the synthesis of novel 2-aryl-imidazo[1,2-a]pyridines has been developed via a one-pot reaction of aromatic aldehydes with 2-amino-5-chloropyridine and tert-butylisocyanide in the presence of I-2 in ethanol at 70 degrees C. The present approach offers the advantages of a clean and simple methodology, high atom-economy, mild conditions, short reaction times, wide substrate scope, low environmental impact and high yield.
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