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TOXICOLOGY LETTERS (2011)
Mono-(2-ethylhexyl) phthalate impairs neurodevelopment: Inhibition of proliferation and promotion of differentiation in PC12 cells
Tian Chen et al.
TOXICOLOGY LETTERS (2011)
Cytochrome P450 enzymes in the brain: emerging evidence of biological significance
Charmaine S. Ferguson et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2011)
Use of an Adult Rat Retinal Explant Model for Screening of Potential Retinal Ganglion Cell Neuroprotective Therapies
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Effects of Chlorpyrifos and Chlorpyrifos-Oxon on the Dynamics and Movement of Mitochondria in Rat Cortical Neurons
Mary-Louise Middlemore-Risher et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Effect of 3D-scaffold formation on differentiation and survival in human neural progenitor cells
Stefanie Ortinau et al.
BIOMEDICAL ENGINEERING ONLINE (2010)
Induction of cell cycle arrest at G1 and S phases and cAMP-dependent differentiation in C6 glioma by low concentration of cycloheximide
Xijun Liu et al.
BMC CANCER (2010)
Reactive microgliosis: extracellular μ-calpain and microglia-mediated dopaminergic neurotoxicity
Shannon Levesque et al.
BRAIN (2010)
Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies
Fernanda Martins Lopes et al.
BRAIN RESEARCH (2010)
Development of a Partition-Controlled Dosing System for Cell Assays
Nynke I. Kramer et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
Organotypic Cultures as Tool to Test Long-Term Effects of Chemicals on the Nervous System
F. Pena
CURRENT MEDICINAL CHEMISTRY (2010)
Polybrominated Diphenyl Ethers Induce Developmental Neurotoxicity in a Human in Vitro Model: Evidence for Endocrine Disruption
Timm Schreiber et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
Species-Specific Differential AhR Expression Protects Human Neural Progenitor Cells against Developmental Neurotoxicity of PAHs
Kathrin Gassmann et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
Effects of Solvents and Dosing Procedure on Chemical Toxicity in Cell-Based in Vitro Assays
Katrin Tanneberger et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2010)
Hypericin, the active component of St. John's wort, inhibits glutamate release in the rat cerebrocortical synaptosomes via a mitogen-activated protein kinase-dependent pathway
Yi Chang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain
Travis J. Rump et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Decylubiquinone Increases Mitochondrial Function in Synaptosomes
Jayne E. Telford et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine
Diana Elinos-Calderon et al.
JOURNAL OF NEURAL TRANSMISSION (2010)
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain
Agnieszka Jankowska-Kulawy et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex
Albert Misko et al.
JOURNAL OF NEUROSCIENCE (2010)
In Vitro Blood-Brain Barrier Models - Latest Advances and Therapeutic Applications in a Chronological Perspective
M. M. B. Ribeiro et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2010)
Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons
Uma Anand et al.
MOLECULAR PAIN (2010)
Resveratrol Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity through Its Anti-Inflammatory Actions
Feng Zhang et al.
MOLECULAR PHARMACOLOGY (2010)
Experimental Models for Assaying Microvascular Endothelial Cell Pathophysiology in Stroke
Susanna Camos et al.
MOLECULES (2010)
Pericytes are required for blood-brain barrier integrity during embryogenesis
Richard Daneman et al.
NATURE (2010)
Direct conversion of fibroblasts to functional neurons by defined factors
Thomas Vierbuchen et al.
NATURE (2010)
Derivation of neural crest cells from human pluripotent stem cells
Gabsang Lee et al.
NATURE PROTOCOLS (2010)
Neural stem cell systems: physiological players or in vitro entities? (vol 11, pg 170, 2010)
Luciano Conti et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Glial Cell Lines: An Overview
George H. De Vries et al.
NEUROCHEMICAL RESEARCH (2010)
Memantine depresses glutamate release through inhibition of voltage-dependent Ca2+ entry and protein kinase C in rat cerebral cortex nerve terminals: An NMDA receptor-independent mechanism
Cheng-Wei Lu et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
Mechanism study of Aconitum-induced neurotoxicity in PC12 cells: Involvement of dopamine release and oxidative damage
Yinglan Zhao et al.
NEUROTOXICOLOGY (2010)
Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2™ cells using automated high-content image analysis
Joshua A. Harrill et al.
NEUROTOXICOLOGY (2010)
Relevance of in vitro neurotoxicity testing for regulatory requirements: Challenges to be considered
Anna K. Bal-Price et al.
NEUROTOXICOLOGY AND TERATOLOGY (2010)
Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: State of the science
Joseph M. Breier et al.
NEUROTOXICOLOGY AND TERATOLOGY (2010)
HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons
Sigeng Chen et al.
PLOS ONE (2010)
Specification and Morphogenesis of Astrocytes
Marc R. Freeman
SCIENCE (2010)
Three-Dimensional Nanofibrous Scaffolds Incorporating Immobilized BDNF Promote Proliferation and Differentiation of Cortical Neural Stem Cells
Malcolm K. Horne et al.
STEM CELLS AND DEVELOPMENT (2010)
Surface strategies for control of neuronal cell adhesion: A review
P. Roach et al.
SURFACE SCIENCE REPORTS (2010)
mRNA Expression is a Relevant Tool to Identify Developmental Neurotoxicants Using an In Vitro Approach
Helena T. Hogberg et al.
TOXICOLOGICAL SCIENCES (2010)
Comparison of Two Blood-Brain Barrier In Vitro Systems: Cytotoxicity and Transfer Assessments of Malathion/Oxon and Lead Acetate
Pergentino Balbuena et al.
TOXICOLOGICAL SCIENCES (2010)
Challenges of using pluripotent stem cells for safety assessments of substances
Kinga Vojnits et al.
TOXICOLOGY (2010)
The in vitro effects of Trolox on methylmercury-induced neurotoxicity
Parvinder Kaur et al.
TOXICOLOGY (2010)
Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
Ruth A. Roberts et al.
TOXICOLOGY (2010)
Differential regulation of axon outgrowth and reinnervation by neurotrophin-3 and neurotrophin-4 in the hippocampal formation
Daniel Hechler et al.
EXPERIMENTAL BRAIN RESEARCH (2010)
Glial-Neuronal Interactions-Implications for Plasticity and Drug Addiction
Sukumar Vijayaraghavan
AAPS JOURNAL (2009)
Sevoflurane and propofol depolarize mitochondria in rat and human cerebrocortical synaptosomes by different mechanisms
R. Bains et al.
ACTA ANAESTHESIOLOGICA SCANDINAVICA (2009)
Induced pluripotent stem cells: a new tool for toxicology screening?
Boon Chin Heng et al.
ARCHIVES OF TOXICOLOGY (2009)
Transcriptional regulation of PSA-NCAM expression by NMDA receptor activation in RA-differentiated C6 glioma cultures
Jaspreet Singh et al.
BRAIN RESEARCH BULLETIN (2009)
Brain endothelial cells and the glio-vascular complex
Hartwig Wolburg et al.
CELL AND TISSUE RESEARCH (2009)
An improved method for isolating Schwann cells from postnatal rat sciatic nerves
Yujun Wei et al.
CELL AND TISSUE RESEARCH (2009)
Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
Krishanu Saha et al.
CELL STEM CELL (2009)
The Potential of Embryonic Stem Cells Combined with -omics Technologies as Model Systems for Toxicology
J. Winkler et al.
CURRENT MEDICINAL CHEMISTRY (2009)
Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing
Michaela Moors et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2009)
A2A adenosine receptor antagonists protect the striatum against rotenone-induced neurotoxicity
Vincenzo Belcastro et al.
EXPERIMENTAL NEUROLOGY (2009)
Extracellular guanosine and GTP promote expression of differentiation markers and induce S-phase cell-cycle arrest in human SH-SY5Y neuroblastoma cells
S. Guarnieri et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2009)
In Situ Mitochondrial Ca2+ Buffering Differences of Intact Neurons and Astrocytes from Cortex and Striatum
Jorge M. A. Oliveira et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
ERK5 Activity Is Required for Nerve Growth Factor-induced Neurite Outgrowth and Stabilization of Tyrosine Hydroxylase in PC12 Cells
Yutaro Obara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons
Xian Xuan Chi et al.
JOURNAL OF CELL SCIENCE (2009)
Phosphatidylinositol 3-kinase activity is required for the induction of differentiation in C6 glioma cells by panaxydol
Jian Hai et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2009)
Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure
Sung W. Choi et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Histone Deacetylase Inhibitors Promote Neurosteroid-Mediated Cell Differentiation and Enhance Serotonin-Stimulated Brain-Derived Neurotrophic Factor Gene Expression in Rat C6 Glioma Cells
Kyoji Morita et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Nicotinic Receptor Stimulation Protects Nigral Dopaminergic Neurons in Rotenone-induced Parkinson's Disease Models
Hiroki Takeuchi et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Molecular and Cellular Mechanisms of Ecstasy-Induced Neurotoxicity: An Overview
Joao Paulo Capela et al.
MOLECULAR NEUROBIOLOGY (2009)
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Stuart M. Chambers et al.
NATURE BIOTECHNOLOGY (2009)
Primary support cultures of hippocampal and substantia nigra neurons
Thomas Fath et al.
NATURE PROTOCOLS (2009)
Microglial responses to dopamine in a cell culture model of Parkinson's disease
Diego Mastroeni et al.
NEUROBIOLOGY OF AGING (2009)
Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71
Gennaro Giordano et al.
NEUROTOXICOLOGY (2009)
Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research
Yuen-Ting Cheung et al.
NEUROTOXICOLOGY (2009)
Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
Laura Lossi et al.
PROGRESS IN NEUROBIOLOGY (2009)
A Human Stem Cell-Based Model for Identifying Adverse Effects of Organic and Inorganic Chemicals on the Developing Nervous System
Leonora Buzanska et al.
STEM CELLS (2009)
Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells
Stefan Schildknecht et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2009)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits neurite outgrowth in differentiating human SH-SY5Y neuroblastoma cells
Jee Eun Jung et al.
TOXICOLOGY LETTERS (2009)
Timing and plasticity in the cerebellum: focus on the granular layer
Egidio D'Angelo et al.
TRENDS IN NEUROSCIENCES (2009)
Investigating Drug-induced Mitochondrial Toxicity: A Biosensor to Increase Drug Safety?
Claudia V. Pereira et al.
CURRENT DRUG SAFETY (2009)
Acute Administration of 3,4-Methylenedioxymethamphetamine Induces Profound Hyperthermia, Blood-Brain Barrier Disruption, Brain Edema Formation, and Cell Injury An Experimental Study in Rats and Mice Using Biochemical and Morphologic Approaches
Hari Shanker Sharma et al.
DRUG ADDICTION: RESEARCH FRONTIERS AND TREATMENT ADVANCES (2008)
In vitro models of neurotrauma
A. Kumaria et al.
BRITISH JOURNAL OF NEUROSURGERY (2008)
Mechanical control of tissue morphogenesis
Parth Patwari et al.
CIRCULATION RESEARCH (2008)
Hydroxylation increases the neurotoxic potential of BDE-47 to affect exocytosis and calcium homeostasis in PC12 cells
Milou M. L. Dingemans et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2008)
How to deal with lipophilic and volatile organic substances in microtiter plate assays
Rent Schreiber et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2008)
Identification of cancer stem-like cells in the C6 glioma cell line and the limitation of current identification methods
Gang Shen et al.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2008)
Enhancement of axonal regeneration by in vitro conditioning and its inhibition by cyclopentenone prostaglandins
David Tonge et al.
JOURNAL OF CELL SCIENCE (2008)
A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis
Andrea V. Leisewitz et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Cerebellar granule cells cultured from adolescent rats express functional NMDA receptors:: an in vitro model for studying the developing cerebellum
R. Lisa Popp et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Activity-Dependent Dynamic Microtubule Invasion of Dendritic Spines
Xindao Hu et al.
JOURNAL OF NEUROSCIENCE (2008)
Pitx3-Transfected Astrocytes Secrete Brain-Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor and Protect Dopamine Neurons in Mesencephalon Cultures
Dehua Yang et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
All-trans retinoic acid arrests neuroblastoma cells in a dormant state.: Subsequent nerve growth factor/brain-derived neurotrophic factor treatment adds modest benefit
Grigore Cernaianu et al.
JOURNAL OF PEDIATRIC SURGERY (2008)
Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells
M. Kathleen Borland et al.
MOLECULAR NEURODEGENERATION (2008)
A rapid Percoll gradient procedure for preparation of synaptosomes
Peter R. Dunkley et al.
NATURE PROTOCOLS (2008)
Differentiation Increases the Resistance of Neuronal Cells to Amyloid Toxicity
Cristina Cecchi et al.
NEUROCHEMICAL RESEARCH (2008)
The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells
D. Jantas et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
VALPROIC ACID INDUCES POLARIZATION, NEURONAL-LIKE DIFFERENTIATION OF A SUBPOPULATION OF C6 GLIOMA CELLS AND SELECTIVELY REGULATES TRANSGENE EXPRESSION
J. A. Benitez et al.
NEUROSCIENCE (2008)
C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (eaac1)
M. G. Bianchi et al.
NEUROSCIENCE (2008)
Preconditioning with NMDA protects against toxicity of 3-nitropropionic acid or glutamate in cultured cerebellar granule neurons
Andrew J. Smith et al.
NEUROSCIENCE LETTERS (2008)
Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype
Toshiaki Kume et al.
NEUROSCIENCE LETTERS (2008)
Memantine prevents MDMA-induced neurotoxicity
C. Chipana et al.
NEUROTOXICOLOGY (2008)
Application of in vitro neurotoxicity testing for regulatory purposes:: Symposium III summary and research needs
Anna K. Bal-Price et al.
NEUROTOXICOLOGY (2008)
Developmental neurotoxicity testing in vitro:: Models for assessing chemical effects on neurite outgrowth
Nicholas M. Radio et al.
NEUROTOXICOLOGY (2008)
Rotenone-induced toxicity is mediated by Rho-GTPases in hippocampal neurons
Monica Sanchez et al.
TOXICOLOGICAL SCIENCES (2008)
Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening
Nicholas M. Radio et al.
TOXICOLOGICAL SCIENCES (2008)
Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells
Joseph M. Breier et al.
TOXICOLOGICAL SCIENCES (2008)
Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing
E. J. Hill et al.
TOXICOLOGY (2008)
Single whole-body exposure to sarin vapor in rats: Long-term neuronal and behavioral deficits
Ettle Grauer et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)
Influence of cytotoxic doses of 4-hydroxynonenal on selected neurotransmitter receptors in PC-12 cells
M. A. Siddiqui et al.
TOXICOLOGY IN VITRO (2008)
Studies with neuronal cells:: From basic studies of mechanisms of neurotoxicity to the prediction of chemical toxicity
C. Sunol et al.
TOXICOLOGY IN VITRO (2008)
The PC12 cell as model for neurosecretion
R. H. S. Westerink et al.
ACTA PHYSIOLOGICA (2008)
In vitro effects of environmentally relevant polybrominated diphenyl ether (PBDE) congeners on calcium buffering mechanisms in rat brain
Cary G. Coburn et al.
NEUROCHEMICAL RESEARCH (2008)
Reprogramming of human somatic cells to pluripotency with defined factors
In-Hyun Park et al.
NATURE (2008)
Neurotoxicity caused by didanosine on cultured dorsal root ganglion neurons
H. Liu et al.
CELL BIOLOGY AND TOXICOLOGY (2008)
Long-term exposure to dieldrin reduces γ-aminobutyric acid type A and N-methyl-D-aspartate receptor function in primary cultures of mouse cerebellar granule cells
Zoila Babot et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2007)
Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: Protective effects of quercetin
Jeferson L. Franco et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2007)
Serotonin stimulates mitochondrial transport in hippocampal neurons
Sigeng Chen et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
An in vitro approach to assess the toxicity of certain food contaminants: Methylmercury and polychlorinated biphenyls
Lucio G. Costa et al.
TOXICOLOGY (2007)
Ecstasy induces apoptosis via 5-HT2A-receptor stimulation in cortical neurons
Joao Paulo Capela et al.
NEUROTOXICOLOGY (2007)
Neurotoxicity mechanisms of thioether ecstasy metabolites
J. P. Capela et al.
NEUROSCIENCE (2007)
Exposure of C6 glioma cells to Pb(II) increases the phosphorylation of p38MAPK and JNK1/2 but not of ERK1/2
Thais Posser et al.
ARCHIVES OF TOXICOLOGY (2007)
Neuronal subtype specification in the cerebral cortex
Bradley J. Molyneaux et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Physicochemical substance properties as indicators for unreliable exposure in microplate-based bioassays
Janet Riedl et al.
CHEMOSPHERE (2007)
Staurosporine differentiation of NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells induces selectivity of NPFF activity towards opioid receptors
Catherine Mollereau et al.
PEPTIDES (2007)
Mechanisms of sodium azide-induced changes in intracellular calcium concentration in rat primary cortical neurons
Silvia Marino et al.
NEUROTOXICOLOGY (2007)
Neurotoxicant-induced inflammatory response in three-dimensional brain cell cultures
F. Monnet-Tschudi et al.
HUMAN & EXPERIMENTAL TOXICOLOGY (2007)
Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons
Teresa Cunha-Oliveira et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Mitochondrial fission is an upstream and required event for Bax foci formation in response to nitric oxide in cortical neurons
H. Yuan et al.
CELL DEATH AND DIFFERENTIATION (2007)
Superior survival and durability of neurons and astrocytes on 3-dimensional aragonite biomatrices
Hagit Peretz et al.
TISSUE ENGINEERING (2007)
Iron supplement prevents lead-induced disruption of the blood-brain barrier during rat development
Qiang Wang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
The tripartite synapse: roles for gliotransmission in health and disease
Michael M. Halassa et al.
TRENDS IN MOLECULAR MEDICINE (2007)
Immediate early gene IEX-1 induces astrocytic differentiation of U87-MG human glioma cells
Fukka You et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticity
Sacha A. Malin et al.
NATURE PROTOCOLS (2007)
Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics
Seongeun Cho et al.
CURRENT NEUROPHARMACOLOGY (2007)
Astroglial cells in development, regeneration, and repair
Flora M. Vaccarino et al.
NEUROSCIENTIST (2007)
Pak1 regulates dendritic branching and spine formation
Kanehiro Hayashi et al.
DEVELOPMENTAL NEUROBIOLOGY (2007)
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells:: Effect of histone deacetylase inhibitors
Jorge M. A. Oliveira et al.
JOURNAL OF NEUROSCIENCE (2006)
Metabolism-dependent mutagenicity of a compound containing a piperazinyl indazole motif: Role of a novel P450-mediated metabolic reaction involving a putative oxaziridine intermediate
Hao Chen et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2006)
Interleukin-1β released by gp120 drives neural death through tyrosine phosphorylation and trafficking of NMDA receptors
Barbara Viviani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Side by side comparison between dynamic versus static models of blood-brain barrier in vitro:: A permeability study
Stefano Santaguida et al.
BRAIN RESEARCH (2006)
Cocaine alters proliferation, migration, and differentiation of human fetal brain-derived neural precursor cells
Shuxian Hu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: Involvement of nicotinic receptors
C. Chipana et al.
NEUROPHARMACOLOGY (2006)
Mitochondrial trafficking to synapses in cultured primary cortical neurons
Diane T. W. Chang et al.
JOURNAL OF NEUROSCIENCE (2006)
Neural stem-like cell line derived from a nonhematopoietic population of human umbilical cord blood
Leonora Buzanska et al.
STEM CELLS AND DEVELOPMENT (2006)
Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine
Teresa Cunha-Oliveira et al.
BRAIN RESEARCH (2006)
Nitric oxide impairs mitochondrial movement in cortical neurons during hypoxia
SA Zanelli et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Development of a solvent-free, solid-phase in vitro bioassay using vertebrate cells
Stephanie K. Bopp et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2006)
Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels
MJ Mahoney et al.
BIOMATERIALS (2006)
Novel role of neuronal Ca2+ sensor-1 as a survival factor up-regulated in injured neurons
TY Nakamura et al.
JOURNAL OF CELL BIOLOGY (2006)
The value of alternative testing for neurotoxicity in the context of regulatory needs
S Coecke et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2006)
Loss of shear stress induces leukocyte-mediated cytokine release and blood-brain barrier failure in dynamic in vitro blood-brain barrier model
L Krizanac-Bengez et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Culturing hippocampal neurons
Stefanie Kaech et al.
NATURE PROTOCOLS (2006)
Neurotoxicity of ecstasy metabolites in rat cortical neurons, and influence of hyperthermia
JP Capela et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia
J. P. Capela et al.
NEUROSCIENCE (2006)
Neuronal differentiation of human umbilical cord blood neural stem-like cell line
Leonora Buzanska et al.
NEURODEGENERATIVE DISEASES (2006)
Allosteric positive interaction of thymol with the GABA(A) receptor in primary cultures of mouse cortical neurons
DA Garcia et al.
NEUROPHARMACOLOGY (2006)
Astrocyte-endothelial interactions at the blood-brain barrier
NJ Abbott et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Inflammation in stroke and focal cerebral ischemia
Judy Huang et al.
SURGICAL NEUROLOGY (2006)
Perturbation of voltage-sensitive Ca2+ channel function by volatile organic solvents
TJ Shafer et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
The natural history of EGFR and EGFRvIII in glioblastoma patients
AB Heimberger et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2005)
Cell migration in 3D matrix
S Even-Ram et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Human cord blood-derived neural stem cell line - Possible implementation in studying neurotoxicity
L Buzanska et al.
TOXICOLOGY IN VITRO (2005)
Local translation of RhoA regulates growth cone collapse
KY Wu et al.
NATURE (2005)
Alcohol impairs astrogliogenesis by stem cells in rodent neurospheres
MC Vemuri et al.
NEUROCHEMISTRY INTERNATIONAL (2005)
Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: Clue for involvement of thyroid hormone receptors
E Fritsche et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2005)
Effects of 6-hydroxydopamine on mitochondrial function and glutathione status in SH-SY5Y human neuroblastoma cells
MA Tirmenstein et al.
TOXICOLOGY IN VITRO (2005)
Accumulation of methylmercury or polychlorinated biphenyls in in vitro models of rat neuronal tissue
CA Meacham et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)
Free radical production induced by methamphetamine in rat striatal synaptosomes
D Pubill et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)
Neurite extension and in vitro myelination within three-dimensional modified fibrin matrices
R Pittier et al.
JOURNAL OF NEUROBIOLOGY (2005)
Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons
MW Ward et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Excitotoxic death induced by released glutamate in depolarized primary cultures of mouse cerebellar granule cells is dependent on GABA(A) receptors and niflumic acid-sensitive chloride channels
Z Babot et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Neurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells
A Jiménez et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
cAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6
H Takanaga et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Stimulation of myelin proteolipid protein gene expression by eicosapentaenoic acid in C6 glioma cells
S Salvati et al.
NEUROCHEMISTRY INTERNATIONAL (2004)
Ras/MEK pathway is required for NGF-induced expression of tyrosine hydroxylase gene
T Suzuki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Selective differentiation of neural progenitor cells by high-epitope density nanofibers
GA Silva et al.
SCIENCE (2004)
Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
T Kondo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
SE Jordt et al.
NATURE (2004)
Neurotoxicity of MDMA (ecstasy):: the limitations of scaling from animals to humans
R de la Torre et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)
S Hori et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Useful cell lines derived from the adrenal medulla
MJ Eaton et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2004)
Toward more useful in vitro toxicity data with measured free concentrations
MB Heringa et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2004)
Characterization of long-term mouse brain aggregating cultures:: Evidence for maintenance of neural precursor cells
CMD Berglund et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2004)
Methionine 35 oxidation reduces toxic and pro-apoptotic effects of the amyloid beta-protein fragment (31-35) on isolated brain mitochondria
F Misiti et al.
NEUROSCIENCE (2004)
First direct demonstration of extensive GABA synthesis in mouse cerebellar neuronal cultures
U Sonnewald et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Accumulation of PBDE-47 in primary cultures of rat neocortical cells
WR Mundy et al.
TOXICOLOGICAL SCIENCES (2004)
Peptide-modified alginate surfaces as a growth permissive substrate for neurite outgrowth
NO Dhoot et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2004)
Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury
JE Kim et al.
NEURON (2004)
Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists
SP Presgraves et al.
NEUROTOXICITY RESEARCH (2004)
Triethyltin-induced stress responses and apoptotic cell death in cultured oligodendrocytes
T Stahnke et al.
GLIA (2004)
Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells
Z Datki et al.
BRAIN RESEARCH BULLETIN (2003)
Endogenous 5-HT, released by MDMA through serotonin transporter- and secretory vesicle-dependent mechanisms, reduces hippocampal excitatory synaptic transmission by preferential activation of 5-HT1B receptors located on CA1 pyramidal neurons
B Mlinar et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals
JD Delcroix et al.
NEURON (2003)
Models of neurotoxicity:: Extrapolation of benchmark doses in vitro
M Goldoni et al.
RISK ANALYSIS (2003)
Expression of trkB in human neuroblastoma in relation to MYCN expression and retinoic acid treatment
A Edsjö et al.
LABORATORY INVESTIGATION (2003)
The protective effect of ganstigmine against amyloid beta25-35 neurotoxicity on chicken cortical neurons is independent from the cholinesterase inhibition
M Windisch et al.
NEUROSCIENCE LETTERS (2003)
Platelet-derived growth factor-b enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
P Guo et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
A novel method of eliminating non-neuronal proliferating cells from cultures of mouse dorsal root ganglia
PL Andersen et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2003)
Blood-brain barrier damage induces release of α2-macroglobulin
L Cucullo et al.
MOLECULAR & CELLULAR PROTEOMICS (2003)
Nestin promotes the phosphorylation-dependent disassembly of vimentin intermediate filaments during mitosis
YH Chou et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Blood-brain barrier disruption in multiple sclerosis
A Minagar et al.
MULTIPLE SCLEROSIS JOURNAL (2003)
Morphologic and neurotoxic effects of ethanol vary with timing of exposure in vitro
TA Lindsley et al.
ALCOHOL (2002)
Prediction of drug transport through the blood-brain barrier in vivo:: A comparison between two in vitro cell models
S Lundquist et al.
PHARMACEUTICAL RESEARCH (2002)
Impact of protein binding on the availability and cytotoxic potency of organochlorine pesticides and chlorophenols in vitro
M Gülden et al.
TOXICOLOGY (2002)
Factors influencing nominal effective concentrations of chemical compounds in vitro:: medium protein concentration
H Seibert et al.
TOXICOLOGY IN VITRO (2002)
Functional expression and localization of P-glycoprotein at the blood brain barrier
R Bendayan et al.
MICROSCOPY RESEARCH AND TECHNIQUE (2002)
Astrocyte-endothelial interactions and blood-brain barrier permeability
NJ Abbott
JOURNAL OF ANATOMY (2002)
Neurological evaluation of toxic axonopathies in rats: Acrylamide and 2,5-hexanedione
RM LoPachin et al.
NEUROTOXICOLOGY (2002)
Ca2+-independent vesicular catecholarnine release in PC12 cells by nanomolar concentrations of Pb2+
RHS Westerink et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease
C Chinopoulos et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Physiology - Cold current in thermoreceptive neurons
G Reid et al.
NATURE (2001)
Factors influencing nominal effective concentrations of chemical compounds in vitro:: cell concentration
M Gülden et al.
TOXICOLOGY IN VITRO (2001)
Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures
AP Balgude et al.
BIOMATERIALS (2001)
Control of synapse number by glia
EM Ullian et al.
SCIENCE (2001)
Regulation of chromogranin biosynthesis by neurotrophic growth factors in neuroblastoma cells
C Weiss et al.
NEUROCHEMISTRY INTERNATIONAL (2001)
Neuroblastoma cell lines - a versatile in vitro model in neurobiology
P Shastry et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2001)
Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation
T Ostenfeld et al.
EXPERIMENTAL NEUROLOGY (2000)
Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models
D Rice et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2000)
Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension
JC Schense et al.
NATURE BIOTECHNOLOGY (2000)
Serum alters the uptake and relative potencies of halogenated aromatic hydrocarbons in cell culture bioassays
EV Hestermann et al.
TOXICOLOGICAL SCIENCES (2000)
Alteration of veratridine neurotoxicity in sympathetic neurons during development in vitro
T Koike et al.
NEUROREPORT (2000)
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