期刊
ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA
卷 26, 期 2, 页码 247-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.coms.2014.02.002
关键词
Osteoradionecrosis; Radiation-induced fibroatrophy; Pentoxifylline; Tocopherol; Clodronate
Managing osteoradionecrosis (ORN) of the facial bones is a challenge in maxillofacial head and neck surgery. Changes in understanding of ORN of the jaws has led to new studies using novel therapeutic modalities to manage this disorder. These treatment regimens may allow medical management to replace major reconstructive surgery for some patients who have already undergone chemoradiotherapy or combined modality therapy for head and neck cancer.
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