Central venous oxygen saturation: analysis, clinical use and effects on mortality

Aims and Objectives: The aim of this literature review was to provide a clear definition of central venous oxygen saturation (ScvO2), highlight the differences between ScvO2 and mixed venous oxygen saturation (SvO2), show how it can be used clinically and the effect central venous oxygen saturation has on mortality. Background: Many articles concentrate on the individual aspects of ScvO2, such as its use in early goal-directed therapy, but few provide a full overview of what it means, how to interpret results and how it can be used clinically. Search strategies: Keywords were searched for including central venous oxygen saturation ScvO2 mixed venous oxygen saturations ScvO2 early goal-directed therapy sepsis and mortality. Where possible only publications within the last 10 years were used but key publications were not excluded if they were out with this time frame. Conclusions: Central venous oxygen saturation (ScvO2) is a very important measurement which can be easily taken in a critical care environment by both medical and nursing staff. It provides an understanding of the patient's oxygen delivery, oxygen consumption and cardiac output. It has a key role within early goal-directed therapy and has been shown to decrease mortality when taken and analysed appropriately. Relevance to clinical practice: This literature review will highlight to nursing staff within the critical care environment the importance of central venous oxygen saturation measurement and interpretation. By raising awareness of the importance of this measurement it is hoped nursing staff will be proactive in both taking this test and analysing the results, therefore facilitating better care for the septic, critically ill patient and improving outcomes for these patients.