期刊
NEUROSCIENCE BULLETIN
卷 29, 期 4, 页码 436-444出版社
SPRINGER
DOI: 10.1007/s12264-013-1365-4
关键词
pyramidotomy; strain differences; contusion; injury models
资金
- NINDS [1R01NS081040-01, 1R21NS082835-01]
- US Army [W81XWH1010737]
- Miami Project to Cure Paralysis
- Buoniconti Fund
- U.S. Department of Defense (DOD) [W81XWH1010737] Funding Source: U.S. Department of Defense (DOD)
With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. in this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.
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