BOLD-MRI cerebrovascular reactivity findings in cocaine-induced cerebral vasculitis

Background An 18-year-old woman presented to a regional stroke center with dysphasia and right hemiparesis 2 days after consuming alchohol and inhaling cannabis and-for the first time-cocaine. Investigations Physical examination, blood tests for inflammatory markers, vasculitis and toxicology screen, echcardiography, electrocardiography, CT scanning, brain MRI, magnetic resonance angiography, magnetic resonance vessel wall imaging, catheter angiography, and correlation of blood oxygen level-dependent (BOLD)-MRI signal intensity with changes in end-tidal partial pressure of carbon dioxide. Diagnosis Cocaine-induced cerebral vasculitis. Management No specific therapy was initiated. The patients vital signs and neurological status were monitored during her admission. Follow-up medical imaging was performed after the patient's discharge from hospital.