期刊
NANOSCIENCE AND NANOTECHNOLOGY LETTERS
卷 3, 期 5, 页码 629-636出版社
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/nnl.2011.1238
关键词
Sol-Gel Process; TiO2 Thin Films; Scanning Electron Microscopy; Antimicrobial Activity; X-Ray Photoelectron Spectroscopy; Fe Additive
资金
- Sri Vishnu College of Pharmacy, Bhimavaram, Andhra Pradesh State, India
- Nano-RAM Technologies, Bangalore, Karnataka State, India
- Spanish MICINN [FIS2009-12964-C05-04, CSD2008-00023]
We prepared thin films composed of pure TiO2 or TiO2 with an Fe additive (at concentrations of 0.2-0.8 wt%) via a simple and cost effective sol gel process, and tested their antifungal properties (against Candida albicans (MTCC-1637), Candida tropicalis (MTCC-184), Candida parapsilosis (MTCC-2509), and Candida glabrata (MTCC-3019) and antibacterial properties (against Staphylococcus faecalis (NCIM-2604) Staphylococcus epidermidis (NCIM-2493), Staphylococcus aureus (NCIL-2122), and Bacillus subtilis (NCIM-2549)). The films were deposited on glass and Si substrates and subjected to annealing at 400 degrees C for 3 h in ambient air. The film structural and morphological properties were investigated by X-ray photoelectron spectroscopy profilometry and scanning electron microscopy, respectively. Antifungal and antibacterial tests were conducted using the drop test method. Among the species examined, Candida albicans (MTCC-1637), and Staphylococcus aureus (NCIL-2122) showed complete colony formation inhibition after exposure for 4 h for the TiO2 loaded with 0.8 wt% Fe thin films. These results indicate that increasing the Fe concentration increased the antimicrobial activity, with complete inhibition of colony formation after 4 h exposure.
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