期刊
MATERIALS
卷 3, 期 3, 页码 1803-1832出版社
MDPI
DOI: 10.3390/ma3031803
关键词
parylene; micropatterning; surface modification; [2.2]paracyclophane; biomaterial; bioactive; biomolecular; nanobiotechnology; microarray; microfluidic
类别
资金
- NIH [DC07489]
Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene peel-off stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensors and biological microenvironments. A variety of substituted precursors enables direct coating of functionalised parylenes onto biomedical implants and microfluidics, providing a convenient method for designing biocompatible and bioactive surfaces. This article will review the emerging role and applications of parylene as a biomaterial for surface chemical modification and provide a future outlook.
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