期刊
ISLETS
卷 2, 期 4, 页码 261-262出版社
LANDES BIOSCIENCE
DOI: 10.4161/isl.2.4.12028
关键词
beta-cell regeneration; bioluminescence; (MIP)-luc mouse; islet; in vivo
In the last five years, bioluminescence has emerged as a vital tool in the non-invasive quantification of beta-cell mass following islet transplantation in murine models. The successes achieved in bioluminescence imaging in islet transplantation has prompted its use in the discipline of beta-cell regeneration. Employing bioluminescence permits quantifying changes in beta-cell mass in an individual mouse over time, which can provide valuable insights into the kinetics of beta-cell regeneration.
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