期刊
GREEN CHEMISTRY LETTERS AND REVIEWS
卷 2, 期 3, 页码 175-179出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/17518250903252260
关键词
Biginelli reaction; microwave synthesis; cost-effective ionic liquid; dihydropyrimidin-2(1H)-ones
资金
- UGC (SAP)
- CSIR New Delhi
A simple, efficient and environmentally friendly process for synthesis of 3,4-dihydropyrimidinones using a one-pot three-component condensation of aromatic aldehydes, beta-dicarbonyl compounds, and urea/thiourea is discussed. The cost-effective, new generation ionic liquid (IL), tri-(2-hydroxyethyl) ammonium acetate was used as both solvent and catalyst. The reactions were carried out using both conventional heating and microwave energy. Application of IL technology with microwave energy represents an attractive and rapid alternative to the conventional acid-base catalyzed thermal processes.
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