相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients
Szu-Hua Pan et al.
LUNG CANCER (2010)
Emerging pulmonary vasculature lacks fate specification
Margaret A. Schwarz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease
Ann E. Tilley et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
John M. L. Ebos et al.
CANCER CELL (2009)
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
Marta Paez-Ribes et al.
CANCER CELL (2009)
Semaphorins and their receptors in lung cancer
Vincent A. Potiron et al.
CANCER LETTERS (2009)
Interfering with multimerization of netrin-1 receptors triggers tumor cell death
F. Mille et al.
CELL DEATH AND DIFFERENTIATION (2009)
A Semaphorin 3A Inhibitor Blocks Axonal Chemorepulsion and Enhances Axon Regeneration
Marisol Montolio et al.
CHEMISTRY & BIOLOGY (2009)
Notch signaling controls the balance of ciliated and secretory cell fates in developing airways
Po-Nien Tsao et al.
DEVELOPMENT (2009)
Notch signaling promotes airway mucous metaplasia and inhibits alveolar development
J. Sawalla Guseh et al.
DEVELOPMENT (2009)
Inhibition of Endothelial Cell Apoptosis by Netrin-1 during Angiogenesis
Marie Castets et al.
DEVELOPMENTAL CELL (2009)
Integrin Acts Upstream of Netrin Signaling to Regulate Formation of the Anchor Cell's Invasive Membrane in C. elegans
Elliott J. Hagedorn et al.
DEVELOPMENTAL CELL (2009)
Molecular Profiling of the Plexinome in Melanoma and Pancreatic Cancer
Asha Balakrishnan et al.
HUMAN MUTATION (2009)
In vitro- and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein
Lori Holle et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2009)
Distinct Biological Roles for the Notch Ligands Jagged-1 and Jagged-2
Kuicheon Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Semaphorin signaling in cancer cells and in cells of the tumor microenvironment - two sides of a coin
Lorena Capparuccia et al.
JOURNAL OF CELL SCIENCE (2009)
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
Martin L. Sos et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Regulatory T Cells Negatively Regulate Neovasculature of Airway Remodeling via DLL4-Notch Signaling
Miao-Tzu Huang et al.
JOURNAL OF IMMUNOLOGY (2009)
To Die or Not to Die, That's the Question - And the Answer May Depend on Netrin-1
Michael P. Schoen et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
Interference With Netrin-1 and Tumor Cell Death in Non-Small Cell Lung Cancer
Celine Delloye-Bourgeois et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
The Slit/Robo System Suppresses Hepatocyte Growth Factor-dependent Invasion and Morphogenesis
Maria Cristina Stella et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
ZEB-1, a Repressor of the Semaphorin 3F Tumor Suppressor Gene in Lung Cancer Cells
Jonathan Clarhaut et al.
NEOPLASIA (2009)
Endothelial EphA receptor stimulation increases lung vascular permeability
Jacqueline Larson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Slits and Roundabouts in cancer, tumour angiogenesis and endothelial cell migration
John A. Legg et al.
ANGIOGENESIS (2008)
Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis
Elena Geretti et al.
ANGIOGENESIS (2008)
Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A
Masashi Narazaki et al.
BLOOD (2008)
Blocking neuropilin-2 function inhibits tumor cell metastasis
Maresa Caunt et al.
CANCER CELL (2008)
Semaphorin 3B Inhibits the Phosphatidylinositol 3-Kinase/Akt Pathway through Neuropilin-1 in Lung and Breast Cancer Cells
Emely Castro-Rivera et al.
CANCER RESEARCH (2008)
A Human Antibody-Drug Conjugate Targeting EphA2 Inhibits Tumor Growth In vivo
Dowdy Jackson et al.
CANCER RESEARCH (2008)
Targeting Slit-Roundabout signaling inhibits tumor angiogenesis in chemical-induced squamous cell carcinogenesis
Li-Jing Wang et al.
CANCER SCIENCE (2008)
Eph-ephrin bidirectional signaling in physiology and disease
Elena B. Pasquale
CELL (2008)
Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity
George A. Wilkinson et al.
DEVELOPMENTAL DYNAMICS (2008)
Netrin-1 and its receptors in tumour growth promotion
Agnes Bernet et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2008)
Neuropilins: a versatile partner of extracellular molecules that regulate development and disease
Katarzyna Adela Uniewicz et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
γ-Secretase Activation of Notch Signaling Regulates the Balance of Proximal and Distal Fates in Progenitor Cells of the Developing Lung
Po-Nien Tsao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors
Roberta Noberini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling
Dana M. Brantley-Sieders et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment
Charlotte Rolny et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Transmembrane domain interactions control biological functions of neuropilin-1
Lise Roth et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
The EphA2 Receptor and EphrinA1 Ligand in Solid Tumors: Function and Therapeutic Targeting
Jill Wykosky et al.
MOLECULAR CANCER RESEARCH (2008)
Somatic mutations affect key pathways in lung adenocarcinoma
Li Ding et al.
NATURE (2008)
A role for VEGF as a negative regulator of pericyte function and vessel maturation
Joshua I. Greenberg et al.
NATURE (2008)
Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
Christian Stockmann et al.
NATURE (2008)
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability
Christopher A. Jones et al.
NATURE MEDICINE (2008)
Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex
Kazue Hashimoto-Torii et al.
NEURON (2008)
Microtubule stabilizing effect of notch activation in primary cortical neurons
G. Ferrari-Toninelli et al.
NEUROSCIENCE (2008)
Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3B
N. Koyama et al.
ONCOGENE (2008)
Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer
Julien Fitamant et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ErbB-2 and met reciprocally regulate cellular signaling via plexin-B1
Jakub M. Swiercz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The semaphorins: versatile regulators of tumour progression and tumour angiogenesis
Gera Neufeld et al.
NATURE REVIEWS CANCER (2008)
Receptor EphA2 activation with ephrinA1 suppresses growth of malignant mesothelioma (MM)
Najmunnisa Nasreen et al.
CANCER LETTERS (2007)
Epigenetic and genetic alterations in netrin-1 receptors UNC5C and DCC in human colon cancer
Sung Kwan Shin et al.
GASTROENTEROLOGY (2007)
Plexin-B1 mutations in prostate cancer
Oscar Gee-Wan Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Promoter hypermethylation of RASSF1A and RUNX3 genes as an independent prognostic prediction marker in surgically resected non-small cell lung cancers
Naoki Yanagawa et al.
LUNG CANCER (2007)
Prognostic implications of netrin-1 expression and its receptors in patients with adenocarcinoma of the pancreas
Bjoern-Christian Link et al.
ANNALS OF SURGICAL ONCOLOGY (2007)
γ-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers
Jun Konishi et al.
CANCER RESEARCH (2007)
Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung
Yuanbin Chen et al.
CANCER RESEARCH (2007)
Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis
S. Rodrigues et al.
ONCOGENE (2007)
Transcriptional network governing the angiogenic, switch in human pancreatic cancer
Amir Abdollahi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mechanisms of adverse effects of anti-VEGF therapy for cancer
T. Kamba et al.
BRITISH JOURNAL OF CANCER (2007)
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
Gavin Thurston et al.
NATURE REVIEWS CANCER (2007)
Cupredoxin-cancer interrelationship: Azurin binding with EphB2, interference in EphB2 tyrosine phosphorylation, and inhibition of cancer growth
Anita Chaudhari et al.
BIOCHEMISTRY (2007)
Notch-1 regulates pulmonary neuroendocrine cell differentiation in cell lines and in transgenic mice
Lin Shan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Netrin signaling leading to directed growth cone steering
Jennifer Round et al.
CURRENT OPINION IN NEUROBIOLOGY (2007)
Transcriptional control of lung morphogenesis
Yutaka Maeda et al.
PHYSIOLOGICAL REVIEWS (2007)
Neuropilins Novel Targets for Anti-Angiogenesis Therapies
Elena Geretti et al.
CELL ADHESION & MIGRATION (2007)
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
Qi Pan et al.
CANCER CELL (2007)
Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells
David Yu Greenblatt et al.
ONCOLOGIST (2007)
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord
Shinjiro Kaneko et al.
NATURE MEDICINE (2006)
Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
Benoit Favier et al.
BLOOD (2006)
Netrins promote developmental and therapeutic angiogenesis
Brent D. Wilson et al.
SCIENCE (2006)
Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts
Quang-De Nguyen et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
Terhi Karpanen et al.
FASEB JOURNAL (2006)
Robo4 signaling in endothelial cells implies attraction guidance mechanisms
S Kaus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Neuronal clues to vascular guidance
S Suchting et al.
EXPERIMENTAL CELL RESEARCH (2006)
Role of the ephrin and Eph receptor tyrosine kinase families in angiogenesis and development of the cardiovascular system
J Zhang et al.
JOURNAL OF PATHOLOGY (2006)
EphB4 controls blood vascular morphogenesis during postnatal angiogenesis
R Erber et al.
EMBO JOURNAL (2006)
Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly
SS Foo et al.
CELL (2006)
Semaphorins command cells to move
RR Kruger et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
EphB2 expression across 138 human tumor types in a tissue microarray: High levels of expression in gastrointestinal cancers
A Lugli et al.
CLINICAL CANCER RESEARCH (2005)
A role for axon guidance receptors and ligands in blood vessel development and tumor angiogenesis
M Klagsbrun et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2005)
The brain within the tumor:: new roles for axon guidance molecules in cancers
A Chédotal et al.
CELL DEATH AND DIFFERENTIATION (2005)
Serum levels of Magic Roundabout protein in patients with advanced non-small cell lung cancer (NSCLC)
M Görn et al.
LUNG CANCER (2005)
EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics
RC Ireton et al.
CURRENT CANCER DRUG TARGETS (2005)
Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers
N Haruki et al.
CANCER RESEARCH (2005)
Neural guidance molecules regulate vascular remodeling and vessel navigation
A Eichmann et al.
GENES & DEVELOPMENT (2005)
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase
F Llambi et al.
EMBO JOURNAL (2005)
Netrin-integrin signaling in epithelial morphogenesis, axon guidance and vascular patterning
SN Nikolopoulos et al.
CELL CYCLE (2005)
Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis
C Garnis et al.
HUMAN MOLECULAR GENETICS (2005)
Cell movements controlled by the Notch signalling cascade during foregut development in Drosophila
B Fuss et al.
DEVELOPMENT (2004)
Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers
C Hafner et al.
CLINICAL CHEMISTRY (2004)
Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells
JG Wohlfahrt et al.
JOURNAL OF IMMUNOLOGY (2004)
Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling
T Toyofuku et al.
NATURE CELL BIOLOGY (2004)
The role of ephrins and Eph receptors in cancer
H Surawska et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2004)
The versatile roles of axon guidance cues in tissue morphogenesis
L Hinck
DEVELOPMENTAL CELL (2004)
The axonal attractant Netrin-1 is an angiogenic factor
KW Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
XW Lu et al.
NATURE (2004)
Slit and robo expression in the developing mouse lung
JM Greenberg et al.
DEVELOPMENTAL DYNAMICS (2004)
Novel role for netrins in regulating epithelial behavior during lung branching morphogenesis
Y Liu et al.
CURRENT BIOLOGY (2004)
Inhibition of tumor growth and angiogenesis by soluble EphB4
G Martiny-Baron et al.
NEOPLASIA (2004)
Noradrenergic neuronal development is impaired by mutation of the proneural HASH-1 gene in congenital central hypoventilation syndrome (Ondine's curse)
L de Pontual et al.
HUMAN MOLECULAR GENETICS (2003)
Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities
L Nie et al.
EMBO JOURNAL (2003)
Expression of genes involved in vascular development and angiogenesis in endothelial cells of adult lung
CJ Favre et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Presenilin-dependent γ-secretase processing of deleted in colorectal cancer (DCC)
Y Taniguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity
B Wang et al.
CANCER CELL (2003)
Expression of VEGF, semaphorin SEMA3F, and their common receptors neuropilins NP1 and NP2 in preinvasive bronchial lesions, lung tumours, and cell lines
S Lantuéjoul et al.
JOURNAL OF PATHOLOGY (2003)
Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung
S Dalvin et al.
GENE EXPRESSION PATTERNS (2003)
p53RDL1 regulates p53-dependent apoptosis
C Tanikawa et al.
NATURE CELL BIOLOGY (2003)
Slit and robo: expression patterns in lung development
MA Anselmo et al.
GENE EXPRESSION PATTERNS (2003)
Recognition of the neural chemoattractant Netrin-1 by integrins alpha 6 beta 4 and alpha 3 beta 1 regulates epithelial cell adhesion and migration
M Yebra et al.
DEVELOPMENTAL CELL (2003)
Disruption of segmental neural crest migration and ephrin expression in Delta-1 null mice
ME De Bellard et al.
DEVELOPMENTAL BIOLOGY (2002)
Temporal and spatial expression of two isoforms of the Dutt1/Robo1 gene in mouse development
K Clark et al.
FEBS LETTERS (2002)
Tumour specific promoter region methylation of the human homologue of the Drosophilia Roundabout gene DUTT1 (ROBO1) in human cancers
A Dallol et al.
ONCOGENE (2002)
Notch signaling induces rapid degradation of achaete-scute homolog 1
V Sriuranpong et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene
J Xian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis
M Kagoshima et al.
GENES TO CELLS (2001)
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors
JY Wu et al.
NATURE (2001)
The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation
C Forcet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Hierarchical organization of guidance receptors: Silencing of netrin attraction by slit through a Robo/DCC receptor complex
E Stein et al.
SCIENCE (2001)
Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells
NW Gale et al.
DEVELOPMENTAL BIOLOGY (2001)
The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain
A Klostermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization
K Ogawa et al.
ONCOGENE (2000)
Notch/Delta expression in the developing mouse lung
LC Post et al.
MECHANISMS OF DEVELOPMENT (2000)
Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos
C Leimeister et al.
MECHANISMS OF DEVELOPMENT (2000)
In silico cloning of novel endothelial-specific genes
L Huminiecki et al.
GENOME RESEARCH (2000)
Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung
T Ito et al.
MECHANISMS OF DEVELOPMENT (2000)
Chromosome 19 translocation, overexpression of Notch3, and human lung cancer
TP Dang et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)
Characterization of the human and mouse HEY1, HEY2, and HEYL genes:: Cloning, mapping, and mutation screening of a new bHLH gene family
C Steidl et al.
GENOMICS (2000)
Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
R Binétruy-Tournaire et al.
EMBO JOURNAL (2000)
Semaphorin SEMA3F localization in malignant human lung and cell lines - A suggested role in cell adhesion and cell migration
E Brambilla et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)