期刊
CELL ADHESION & MIGRATION
卷 3, 期 2, 页码 179-181出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/cam.3.2.8036
关键词
integrin; fibronectin; migration; cytoskeleton; dynamics
类别
资金
- Dutch Cancer Society [UL 2006-3521]
When cells are stimulated to move, for instance during development, wound healing or angiogenesis, they undergo changes in the turnover of their cell-matrix adhesions. This is often accompanied by alterations in the expression profile of integrins-the extracellular matrix receptors that mediate anchorage within these adhesions. Here, we discuss how a shift in expression between two different types of integrins that bind fibronectin can have dramatic consequences for cell-matrix adhesion dynamics and cell motility.
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