Reticulated Pd(II)/Cu(I) cyclodextrin complexes as recyclable green catalyst for Sonogashira alkynylation

A Pd/Cu loaded polymeric cyclodextrin catalyst was easily prepared via in situ reticulation with diisocyanates under sonochemical conditions. Excellent yields were observed for Sonogashira reactions carried out in water and glycerol and the catalyst could easily be recovered and reused three times without a significant loss in catalytic activity.