期刊
BIOMEDICAL OPTICS EXPRESS
卷 5, 期 3, 页码 713-727出版社
OPTICAL SOC AMER
DOI: 10.1364/BOE.5.000713
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资金
- EyeSight Foundation of Alabama
- International Retina Research Foundation [5R21EY021903]
- Songs for Sight, Buck Trust of Alabama [R01EY06109]
- Research to Prevent Blindness
- Buck Trust of Alabama
- NIH [P30 EY003039]
Subretinal drusenoid deposits (SDD), a recently recognized lesion associated with progression of age-related macular degeneration, were imaged with adaptive optics scanning laser ophthalmoscopy (AO-SLO) and optical coherence tomography (AO-OCT). AO-SLO revealed a distinct en face structure of stage 3 SDD, showing a hyporeflective annulus surrounded reflective core packed with hyperreflective dots bearing a superficial similarity to the photoreceptors in the unaffected retina. However, AO-OCT suggested that the speckled appearance over the SDD rendered by AO-SLO was the lesion material itself, rather than photoreceptors. AO-OCT assists proper interpretation and understanding of the SDD structure and the lesions' impact on surrounding photoreceptors produced by AO-SLO and vice versa. (C) 2014 Optical society of America
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