期刊
BIOMEDICAL OPTICS EXPRESS
卷 3, 期 7, 页码 1565-1578出版社
OPTICAL SOC AMER
DOI: 10.1364/BOE.3.001565
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资金
- Derham Green Fund
- David & Wilma Keath Family Prescribed Private Fund
- SIRF scholarship from the University of Western Australia
- Cancer Council Western Australia
- National Breast Cancer Foundation, Australia
- National Breast Cancer Foundation [NC-12-19] Funding Source: researchfish
We present a high-resolution three-dimensional position tracking method that allows an optical coherence tomography (OCT) needle probe to be scanned laterally by hand, providing the high degree of flexibility and freedom required in clinical usage. The method is based on a magnetic tracking system, which is augmented by cross-correlation-based resampling and a two-stage moving window average algorithm to improve upon the tracker's limited intrinsic spatial resolution, achieving 18 mu m RMS position accuracy. A proof-of-principle system was developed, with successful image reconstruction demonstrated on phantoms and on ex vivo human breast tissue validated against histology. This freehand scanning method could contribute toward clinical implementation of OCT needle imaging. (C) 2012 Optical Society of America
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