期刊
BIOMEDICAL OPTICS EXPRESS
卷 1, 期 2, 页码 414-424出版社
OPTICAL SOC AMER
DOI: 10.1364/BOE.1.000414
关键词
-
资金
- Scottish University Life Sciences Alliance (SULSA)
- UK Engineering and Physical Sciences Research Council (EPSRC)
- SUPA
We use Digital Holographic Microscopy to study dynamic responses of live cells to femtosecond laser cellular membrane photoporation. Temporal and spatial characteristics of morphological changes as well as dry mass variation are analyzed and compared with conventional fluorescent assays for viability and photoporation efficiency. With the latter, the results provide a new insight into the efficiency and toxicity of this novel optical method of drug delivery. In addition, quantitative phase maps reveal photoporation related sub-cellular dynamics of cytoplasmic vesicles. (C) 2010 Optical Society of America
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据