4.6 Article

An efficient and greener protocol towards synthesis of unsymmetrical N,N′-biphenyl urea

期刊

ARABIAN JOURNAL OF CHEMISTRY
卷 6, 期 4, 页码 423-427

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ELSEVIER
DOI: 10.1016/j.arabjc.2011.01.030

关键词

Urea; Isocyanate; Thiourea; Aqueous medium; Carbamate

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A simple and efficient route for the synthesis of Unsymmetrical N,N'-diphenyl urea have been developed in aqueous medium under base and catalyst free condition from corresponding substituted isocyanate and amines. The remarkable key feature of the reaction includes the use of water as an inexpensive and environmentally benign reaction medium, absence of base and any additional catalyst, and easy isolation of the product. (C) 2011 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.

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