期刊
ACS COMBINATORIAL SCIENCE
卷 20, 期 10, 页码 573-578出版社
AMER CHEMICAL SOC
DOI: 10.1021/acscombsci.8b00071
关键词
cyclization; indole; Lewis acid; 1H-pyrazole; ring-opening
资金
- Science and Engineering Research Board, Govt. of India [EMR/2016/005008]
An unusual transformation of indoles to pyrazoles via an aromatic ring-opening strategy has been developed. The salient feature of this strategy involves the C2-N1 bond opening and concomitant cyclization reaction of the C2=C3 bond of the indole moiety with the tosylhydrazone, which proceeds under transition-metal and ligand free conditions. This ring-opening functionalization of indoles provides a wide scope of differently substituted pyrazoles.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据