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2-Methylindole as an Indicative Nucleophile for Developing a Three-Component Reaction of Aldehyde with Two Different Nucleophiles

期刊

ACS COMBINATORIAL SCIENCE
卷 16, 期 6, 页码 287-292

出版社

AMER CHEMICAL SOC
DOI: 10.1021/co500010x

关键词

2-methylindole; indicative nucleophile; three-component reaction

资金

  1. National Natural Science Foundation of China [21373093, 21173089]
  2. Cooperative Innovation Center of Hubei Province
  3. Chutian Scholar Program of the Hubei Provincial Government

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2-Methylindole was used as an indicative nucleophile for rapid screening of MCRs of aldehydes with two different nucleophiles. By removal of some samples that have characteristic color associated with the generation of di(indolyOmethane derivatives the difficulties encountered in the product analysis were alleviated significantly.

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